7 - chlamydia and chlamoydophila Flashcards
chlamydiaceae
tiny gram negatives with no peptidoglycan cell wall
obligate intracellulars
chlamydiaceae gram stain
not seen - no peptidoglycan cell wall
also not responsive to beta lactic antibiotics
chlamydiaceae growing conditions
○ Obligate intracellular parasites
§ Can only grow in living cells
§ Energy parasites - cannot produce their own energy but rely on hots cell’s energy producing apparatus
§ Will not grow on artificial media (eg. Agar plates)
○ Chlamydia trachomatis causes
chlamydia,
trachoma,
lymphogranuloma venereum
chlamydia
□ Worlds most commonly sexually transmitted disease
chlamydia in males
® Urethritis
® Epididymitis
® Prostatitis
chlamydia in females
® Urethritis
® Cervicitis
® Upper genital tract infection (PID - pelvic inflammatory disease)
® The latter is a major cause of infertility
® May be asymptomatic yet still lead to infertility
trachoma
□ The worlds leading cause of blindness
trachoma pathology
® Conjunctival follicles, inflammation
® Scarring and contraction
® Eyelashes turned in, damage to cornea
® Scarring of cornea and blindness
LGV - lymphogranuloma venerum
□ A sexually transmitted disease of he tropics
® Northern australia
□ Increasingly seen as a cause of prostitis in male homosexuals
lymphogranuloma centrum features
® Genital papule, ulcer
® Enlargement of inguinal lymoh nodes
® Inguinal inflammatory masses draining pus
® Chronic relapsing course
® Scarring and deformity of genitals and surrounding tissue
□ Elephantiasis may result from lymphatic damage
chlamydia pneumoniae
§ A relatively recently discovered respiratory pathogen
§ Causes mainly lower respiratory tract infection
□ Highest incidence in the elderly
chlamoydophila psittaci
§ This bacterium is a pathogen of psittacine birds (parrots) and other birds and mammals
§ Causes parrot fever - psittacosis or ornithosis
chlamoydophila psittaci causes
parrot fever or psittacosis or ornithosis
parrot fever symptoms
□ Nasal discharge □ Breathing difficulty □ Lethargy □ Weight loss □ Depression