4, 4.1 Flashcards

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1
Q

3 beta lactamase producing gram negative rods

A
  1. ESBLs - extended Spectrum Beta-lactamases
    1. AmpC beta lactamases
    2. Carbapenemases
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2
Q
  • Helical rods
A

○ Genus helicobacter

○ Genus campylobacter

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3
Q

Curved, comma shaped

A

○ Genus vibrio

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4
Q

12 enterobacteriaceae

A
Escherichia 
Proteus 
Citrobacter 
Providencia 
Edwardsiella 
Serratia 
Enterobacter 
Salmonella 
Shigella 
Klebsiella 
Morganella 
Yersinia
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5
Q

3 qualities of enterobacteriaceae

A
  1. Ferments glucose
    1. They are negative in the oxidase test
    2. They are nitrate positive
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6
Q

5 disease associations of enterobacteriaceae

A
UTI 
antibiotic resistant nosocomial infections 
diarrhoeal illness 
typhoid fever 
plague
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7
Q

cystitis

A

Bladder infections

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8
Q

pylonephritis

A

Kidney infections

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9
Q

2 types of UTI

A

○ Bladder infections - cystitis

○ Kidney infections - pylonephritis

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10
Q

UTIs result from

A

○ Result from bacteria of bowel origin gaining access to the distal urethra and ascending the urinary tract

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11
Q

enterobacteriaceae are commensals of

A

the human bowel

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12
Q

uropathogenic strains of enterobacteriaceae

A

§ Posses virulence factors which enable them to colonise the urethra and survive in the urinary tract

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13
Q

second most common cause of UTIs in the community

A

§ Proteus mirabilis is the second most common cause of UTIs in the community

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14
Q

debilitated patients susceptible to antibiotic resistant nosocomial infections

A

§ Intravenous catheters - breach the skin
§ Endotracheal tubes - bypass the defences of the upper airways
§ Urinary catheters - bypass the defences of the urinary tract
§ Surgery - with or without foreign devices left in place, breaches the skin and exposes normally sterile body sites

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15
Q

6 genera of antibiotic resistant nosocomial infections

A
§ Enterobacter 
			§ Serratia 
			§ Klebsiella 
			§ Proteus 
			§ Morganella 
			§ Providencia
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16
Q

types of hospital antibiotic resistant infections

A

§ Pneumonia - often associated with mechanical ventilator use
§ UTI - often associated with catheterisation if the urethra and bladder
§ Blood stream infections - often associated with intravenous cannulas
§ Surgical wound infections
§ Orthopaedic infections

17
Q

EHEC

A

enterohaemorrhagic E coli

18
Q

EPEC

A

Enteropathogenic E coli

19
Q

EIEC

A

Enteroinvasive E coli

20
Q

ETEC

A

Enterotoxigenic E coli

□ Travelers diarrhea

21
Q

§ EaggEC -

A

Enteroaggregative E coli

22
Q

strains of eschericia coli causing diarrhoeal illness

A

§ Produce diarrhoea by different mechanisms and the appearance of the faeces may give a clue as to the cause

23
Q

species that infects lymph nodes within the mesentery, producing a pain which can mimic appendicitis in diarrhoea illness

A
  • Yersinia enterocolitica
24
Q
  • Yersinia enterocolitica
A

produces diarrhoeal illness

§ Also infects lymph nodes within the mesentery, producing a pain which can mimic appendicitis

25
Q

2 species of genus salmonella

A

§ S enterica

§ S bongori

26
Q

serotypes of salmonella

A

□ More than 2000 different serotypes
□ Typhoidal serotypes
□ Non-typhoidal serotypes
® Cause self limiting diarrhea

27
Q

non-typhoidal serotypes of salmonella

A

cause self limiting diarrhoea

28
Q
  • Genus shigella
A

§ Causes bacillary dysentery

§ Faeces contain blood and pus due to inflammatory process in the bowel wall

29
Q
  • Genus shigella
A

§ Causes bacillary dysentery

§ Faeces contain blood and pus due to inflammatory process in the bowel wall

30
Q

cause of diarrhoea with blood and pus

A

genus shigella

31
Q

another name for typhoid fever

A

enteric fever

32
Q

2 serotypes of typhoid fever

A

§ Salmonella typhi

§ Salmonella paratyphi

33
Q

2 serotypes causing typhoid fever

A

salmonella typhi and paratyphoid

34
Q

typhoid fever

A
  • Bacteria in this disease may be found in the bloodstream and in lymphoreticular tissue
    - Systemic disease not diarrhoeal disease