11.4 - deep seated mycoses

Question 1

deep seated mycoses

Answer 1

fungal infections that affect internal body organs

caused by fungi that are virulent enough to cause disease in hints without impaired immunity

Question 2

5 deep seated mycoses

Answer 2

Cryptococcosis
blastomycosis
coccidiodomycosis
paracoccidioidomycosis
histoplasmosis
last 4 are endemic mycoses

Question 3

crypto coccus neoformans and gatti

Answer 3

a yeast characterised by having a very large capsule

can be visualised using India ink

Question 4

cryptococcus neoformans is found in

Answer 4

pigeon droppings

Question 5

crypto coccus gattii is found in

Answer 5

found in eucalyptus trees

Question 6

primary infection with crytococcus occurs by

Answer 6

inhalation, usually asymptomatic

Question 7

disease with cryptococcus may occur in

Answer 7

immunocompetent hosts - gatii

immunocompromised hosts - neoformans

Question 8

presentations of crypto coccus neoformans

Answer 8

pulmonary cryptococcosis - a spectrum of features with a propensity to metastasise to the brain
CNS cryptococcosis - meningoencephalitis, acute or insidious onset
disseminated cryptococcosis - nodular skin lesions, bone lesions, virtually any organ

Question 9

endemic deep seated mycoses

Answer 9

blastomycosis
coccidiodomycosis
paracoccidiodomycosis
histoplasmosis

Question 10

endemic deep seated mycosis

Answer 10

environmental fungi
dimorphic - mould in nature, yeast in host
acquired by inhalation of spores
most infections asymptomatic or mild respiratory symptoms
severity determined by infective dose and immune status
flu like illness and severe pneumonia
mucocutaneous pesions
brain, genitourinary, bone