6.7,8: Large Scale Mutations Flashcards
1
Q
What are large scale mutations?
A
Mutations that affect chromosomes
2
Q
What are the 5 types of large scale mutations?
A
- nondisjunction
- translocation
- inversions
- duplications
- Deletions
3
Q
What is nondisjunction?
A
- when chromosomes do not separate properly in meiosis
4
Q
What does nondisjunction result in?
A
- the incorrect number of chromosomes
Ex, Down syndrome
5
Q
What is translocation?
A
- a segment of one chromosome moves to another
6
Q
What is inversion?
A
A segment is reversed (180 degrees)
Ex. (ABCDE) becomes (ABCED)
7
Q
What are duplications?
A
A segment is repeated
Ex. (ABCDE) becomes (ABABCDE)
8
Q
What are deletions?
A
A segment is lost
