6.2a Development of the CNS Flashcards
Process by which the neural plate forms the neural tube
Neurulation
Length of the entire process of neural fold formation, elevation, closure (in days)
28 Days
CNS development starts at the ___ (in weeks)
3rd week
Elevation on the lateral edges of the thickened neural plate
Neural folds
The closure of the neural tube begins at the
Middle part, approximately at the cervical region or the 5th somite
Day of closure of anterior and posterior neuropore
Day 25 and Day 28, respectively
Lining that comprises the neuroepithelial layer
Pseudostratified epithelium
Cells that form the mantle layer
Neuroblasts
Origin of the gray matter of the spinal cord
Mantle layer
__ plate is the dorsal thickening of the neural tube which contain dorsal sensory horn cells
Alar plate
__ plate is the ventral thickeing of the neural tube which contain ventral motor horn cells that eventuall becomes the motor area
Basal Plate
What is the longitudinal groove that marks the boundary between the alar and basal plates
Sulcus Limitans
The intermediate horn is the accumulation of neurons between the ventral motor horn and dorsal sensory horn; this is only present in the __ and __ of the spinal cord
Thoracic and upper lumbar levels of the spinal cord
The outermost layer of the spinal cord and forms the white matter of the spinal cord
Marginal layer
The axons of neurons in the basal plate break through the marginal zone and become collectively known as __
Ventral motor root of the spinal nerve
Axons of neurons in the alar plate form
Association neurons
These suporting cells are formed from neuroepithelial cells after the production of neuroblasts ceases
Gliablasts
Glial cells that mirated to the mantle layer become the
Protoplasmic and fibrillar astrocytes
Glial cells that migrated to the marginal layer that form myelin sheaths become the ____
Oligodendroglial cells
Origin of microglial cells
Vascular mesenchyme
When the neuroepthelial cells cease to produce neuroblasts and gliablasts, they differentiate into __
ependymal cells
These cells form the lining of the central canal of the spinal cord and the ventricles
Ependymal cells
Two processes of sensory ganglia and structures they form
Centrally-growing processes: dorsal sensory root of spinal nerve
Peripherally-growing processes: join with the ventral motor roots to form the trunk of the spinal nerve
Termination of the spinal cord at birth and during adult life
Birth: L2-L3
Adult: L1-L2
Threadlike extension of pia mater at the end of the spinal cord
Filum terminale
Collection of nerve fibers below the terminal end of the cord
Cauda Equina
Level of needle insertion during lumbar puncture
L4-L5
Location of cervical flexure
Between hindbrain and spinal cord
Location of cephalic flexure
Mesencephalon
Secondary brain vesicle origin of lateral ventricle
Telencephalon
Secondary brain vesicle origin of 3rd ventricle
Diencephalon
Secondary brain vesicle origin of Aqueduct of midbrain or Sylvius
Mesencephalon
Secondary brain vesicle origin of upper part of 4th ventricle
Metencephalon
Secondary brain vesicle origin of lower part of 4th ventricle
Myelencephalon
Secondary brain vesicle origin of medulla oblongata
Myelencephalon
Secondary brain vesicle origin of pons and cerebellum
Metencephalon
Secondary brain vesicle origin of Thalamus, hypothalamus, pineal body, infundibulum
Diencephalon
Secondary brain vesicle origin of cerebral hemispheres, basal ganglia
Telecephalon
Secondary brain vesicle origin of hippocampus
Telencephalon
Location of the pontine flexure
Between the metencephalon and myelencephalon
Origin of the lateral ventricles
Cavity of the cerebral hemispheres
Serves as the structure of communication of each lateral ventricle with the third ventricle
Interventricular foramina of Monro
Origin of the third ventricles
Cavity of diencephalon
Origin of aqueduct of sylvius
Lumen of mesencephalon
Connects third and fourth ventricles
Aqueduct of Sylvius
Origin of the fourth ventricles
Cavity of the rhombencephalon
3 motor nuclei groups of the myelencephalon
Medial somatic efferent: cephalic continuation of the anterior horn cells, supplies the tongue muscles
Intermediate SVE: striated muscles of pharyngeal arches
Lateral GVE: involuntary musculature of the respiratory tract, intestinal tract, and heart
The metencephalon forms the
Cerebellum
Pons
Longitudinal elevation of the alar plate of the midbrain that function as correlation and reflex center for visual impulses
Anterior (superior) colliculus
Longitudinal elevation of the alar plate of the midbrain that function as synaptic relay station for auditory reflexes
Posterior (inferior) colliculus
The hypothalamic sulcus divides the alar plate into
Thalamus and hypothalamus
Origin of the thalamus (__ region of __ plate)
Dorsal region of the alar plate of the prosencephalon
origin of the hypothalamus (__ region of __ plate)
Ventral region of the alar plate
Distinct protuberance on ventral surface of the hypothalamus on each side of the midline
Mamillary body
Neural tube defect that involves incomplete development of the vertebral arches with or without defects of the underlying neural tube
Spina bifida
A preventive measure for spina bifida
Taking folic acid
Refers to a spectrum of abnormalities in which a loss of midline structures result sin malformations of the brain and face
Holoprosencephaly (HPE)
A rare disorder in which large clefts occur in the cerebral hemispheres, somtimes causing a loss of brain tissue
Schizencephaly