6.1.8 Flashcards
What is glaucoma?
A condition that affects your eyes, causing damage to the optic nerve due to high pressure inside the eye or normal pressure.
Glaucoma often leads to vision loss, particularly in peripheral vision, and typically shows no symptoms until significant damage has occurred.
What are the primary risk factors for glaucoma?
- Age
- Family History
- Elevated Intraocular Pressure (IOP)
- Ethnicity
- Other Eye Conditions
- Medications
- Other Systemic Conditions
These factors significantly increase the risk of developing glaucoma.
How does age affect the risk of glaucoma?
The risk increases with age, especially after 40, peaking at 70-80 years for open-angle glaucoma (OAG).
Incidence increases rapidly after age 60.
What is the significance of family history in glaucoma risk?
A strong family history, especially in first-degree relatives, significantly increases the risk of developing glaucoma.
Genetic predisposition is documented in both primary open-angle glaucoma (POAG) and angle-closure glaucoma (ACG).
What is ocular hypertension (OHT)?
An elevated intraocular pressure (greater than 21 mmHg) that is a major risk factor for glaucoma, though not all with OHT will develop glaucoma.
An IOP consistently above the normal range can damage the optic nerve over time.
Which ethnicities are associated with a higher risk of glaucoma?
- African-Caribbean and African descent
- Asian populations (higher risk of angle-closure glaucoma)
- Latino populations (higher risk for glaucoma, especially angle-closure types)
Ethnicity plays a significant role in glaucoma risk.
What ocular conditions increase the risk of developing glaucoma?
- Myopia
- Diabetes
- Previous eye injury
- High refractive errors
- Cataracts
- Optic nerve abnormalities
These conditions indicate higher vulnerability to glaucoma.
What medications are known to increase the risk of glaucoma?
Chronic use of corticosteroids, which can raise IOP and lead to secondary glaucoma, commonly referred to as steroid-induced glaucoma.
This includes topical, systemic, or inhaled corticosteroids.
What systemic conditions may increase glaucoma risk?
- High blood pressure
- Diabetes
- Vascular issues
- Sleep apnea
These conditions can affect ocular perfusion and increase the risk of glaucoma.
What are the key clinical examination findings for open-angle glaucoma?
- Optic nerve head changes (cupping, pallor, notching)
- Visual field defects (peripheral loss)
- Elevated IOP
- Wide-open anterior chamber angle (gonioscopy)
These findings help diagnose open-angle glaucoma.
What are the symptoms of closed-angle glaucoma?
- Painful red eye
- Halos around lights
- Nausea/vomiting
- Corneal edema
- Mid-dilated pupil that is non-reactive to light
Closed-angle glaucoma is a medical emergency requiring immediate attention.
When should a patient be referred for glaucoma?
- Elevated IOP (above 21 mmHg) with risk factors
- Suspicious optic nerve changes
- Visual field defects suggestive of glaucoma
- Clinical presentation of angle-closure glaucoma
- Normal-tension glaucoma with optic nerve damage risk
Referral is crucial for timely management.
What steps are crucial in managing suspected glaucoma?
- Monitor IOP regularly
- Optic nerve head imaging
- Visual field testing
- Referral for comprehensive glaucoma assessment
- Management of diagnosed conditions
These steps help in early detection and management.
What is optic disc cupping?
An increase in the depth or size of the central depression (the cup) in the optic disc, often seen in glaucoma.
A normal cup-to-disc ratio is typically 0.3 or lower; in glaucoma, this ratio increases, often reaching values of 0.6 or higher.
What does optic disc pallor indicate in glaucoma?
A pale appearance of the optic disc due to loss of nerve fibers and diminished blood flow to the optic nerve.
This is usually a sign of chronic damage in glaucoma.
What is notching of the optic disc?
Localized loss of optic nerve tissue at the rim of the optic disc, particularly at the edges of the cup.
This occurs due to asymmetric nerve fiber loss affecting specific areas of the optic nerve head.
What are the treatment options for glaucoma?
- Eye drops to lower eye pressure
- Laser treatment to improve fluid drainage
- Surgery (trabeculectomy, tube shunt) if necessary
Treatment depends on the severity and type of glaucoma.
What is trabeculectomy?
A surgery performed when eye pressure is too high despite medication or laser treatment, creating a new drainage hole in the eye.
It is effective in reducing eye pressure and requires regular follow-ups.
What is tube shunt surgery?
A procedure involving placement of a small tube in the eye to help fluid drain properly, used in more complicated cases.
It may require post-operative eye drops for healing.
What is laser peripheral iridotomy?
A laser treatment for angle-closure glaucoma that creates a hole in the iris to allow fluid to drain properly.
This quick procedure prevents serious increases in eye pressure.
What is laser trabeculoplasty?
A laser procedure for open-angle glaucoma that helps the drainage system function better to lower eye pressure.
Laser is used to target cells in trabecular meshwork. Enegery is absorbed by pigmented cells which improves drainage
What symptoms indicate the urgency of treatment for angle-closure glaucoma?
- Intense eye pain
- Nausea
- Blurry vision
Immediate treatment is crucial to prevent permanent vision loss.
What is the optic cup?
The optic cup is a central depression in the optic disc.
How does the optic cup change in glaucoma?
In glaucoma, the loss of nerve fibers leads to the characteristic appearance of a notch in the optic disc rim.