6.1.7: Acid Anhydrides

Question 1

Acid anhydride

Answer 1

Made from two identical carboxylic acid molecules which are joined together by an oxygen with the carbonyl groups on each side and water is released

Question 2

Acid anhydride naming

Answer 2

• oic anhydride

Question 3

Acid anhydride vs acyl chlorides

Answer 3

compounds that react in a similar way

Question 4

Reactions of acid anhydrides compared to acyl chlorides

Answer 4

less vigorous and a carboxylic acid is produced instead of HCl

Question 5

Acid anhydride reactions with water

Answer 5

produce a carboxylic acid (often 2 of the same one)

Question 6

Acid anhydride reactions with alcohols

Answer 6

produce a carboxylic acid and an ester

Question 7

Acid anhydride reactions with ammonia

Answer 7

produce a carboxylic acid and an amide

Question 8

Acid anhydride reactions with primary amines

Answer 8

produce a carboxylic acid and an N-substituted amide

Question 9

Aspirin

Answer 9

An ester made from salicylic acid and

ethanoic anhydride or ethanoyl chloride

Question 10

Is ethanoic anhydride or ethanoyl chloride used to make aspirin in industry?
why?

Answer 10

ethanoic anhydride
cheaper
safer as its less corrosive, doesn’t produce HCl and reacts more slowly with water