53 SQ/Systemic Fungal Dz Flashcards
How do SQ mycoses typically begin?
Injuries
Where are oomycosis found?
In the water
What causes the disease pythium, and what kind of inflammation does it produce?
Oomycoses; pyogranulomatous
What disease is clinically identical to pythium?
Lagenidium
Phaeohyphomycosis is caused by _____ (dematiaceous/hyaline) fungi.
Dematiaceous
What fungal disease has greatly affected the fish and caviar industry?
Systemic phaeohyphomycosis
What kind of lesions do Cryptococcus neoformans create and in what tissues?
Ulcerative lesions in the mucous membranes of upper resp tract, CNS (meninges), and eye (chorioretinitis).
What animal is most commonly affected by cryptococcus neoformans?
Cats
Does cryptococcus cause a lot of inflammation, and why or why not?
No, because it stimulates Tregs
What are the reservoirs of cryptococcus?
Dust/dirt, amoebas, and pigeon droppings
T or F: systemic mycoses are rarely dimorphic.
F
How are systemic fungal infections typically acquired?
Inhalation
T or F: systemic mycoses are usually noncontagious.
T
What kind of inflammation/lesions do systemic mycoses tend to cause?
Pyogranulomatous
Is coccidioides dimorphic?
Yes
What disease do coccidioides cause?
Valley fever
What two domestic animals are most commonly infected with coccidioides?
Dogs and horses
Coccidiomycosis reproduces by producing _____
Arthroconidias
What lesions would you find on necropsy from a dog with valley fever?
Pulmonary lesions and osteomyelitis
T or F: histoplasma is dimorphic
T
What variety of Histoplasma is found worldwide?
Histoplasma var. capsulatum
Histoplasma prefers an _____ (acidic/alkaline) environment.
Alkaline
What is the relationship between histoplasma and population density?
Histoplasma is associated with high density populations
What are the reservoirs of histoplasma?
Birds (passive carriers) and bats (intestinal infection)
During infection, what type of cells do histoplasma attach to?
Macrophages in the lung
What kind of inflammation does histoplasma cause?
Suppurative to granulomatous
What domestic animal is most infected by histoplasma?
Dogs
T or F: Blastomyces is dimorphic
T
Where in North America is Blastomyces dermatitidis found?
Eastern third of the continent
What mammals are most often affected by blastomycosis?
Humans and dogs
What kind of Aspergillus is most common in animals and humans?
A. fumigatus
What kind of disease does Aspergillus cause in birds?
Resp tract infection, mortality aprox 50%
What kind of disease does Aspergillus cause in ruminants?
Bovine abortions in late pregnancy, mastitis
