47 WNV

Question 1

WNV is enveloped/non-enveloped.

Answer 1

Enveloped

Question 2

What kind of genome does WNV have?

Answer 2

Positive sense ssRNA

Question 3

When and where was WNV first discovered in the US?

Answer 3

1999 in the Bronx zoo

Question 4

What is the amplifying host for WNV and why?

Answer 4

Birds because they get a very high viremia

Question 5

What is the vector for WNV?

Answer 5

Mosquitos

Question 6

How is WNV monitored in California?

Answer 6

-Clinically confirmed human or equine infection
-Virus isolation or viral RNA in mosquitoes or dead birds
-Sentinel chicken seroconversion
-Wild bird seroconversion

Question 7

What is MIR?

Answer 7

Minimum infection rate–how often the virus is found in its vector species

Question 8

What time of year is the highest risk for WNV and why?

Answer 8

Spring/summer due to high temps

Question 9

T or F: WNV is neuroinvasive.

Answer 9

T

Question 10

Approximately what percentage of horses infected with WNV get “west nile fever” or CNS disease?

Answer 10

~20% West Nile Fever, <1% CNS dz

Question 11

Are neurologic deficits permanent if a horse recovers from WNV?

Answer 11

They can be

Question 12

Is WNV reportable?

Answer 12

Yes

Question 13

How is WNV diagnosed?

Answer 13

Serology, PCR, ELISA

Question 14

Describe the WNV vaccine protocol.

Answer 14

2-3 doses in the primary series, then an annual booster each spring to achieve high titers for the warm season