4.3 Efficiency & regulation of cell. resp. Flashcards
Metabolic rate
The amount of energy that is expended per unit time in an organism
Basal metabolic rate (BMR)
Metabolic rate of an organism at rest
Beta-oxidation
A process in which fatty acids are broken down into acetyl-coA through catabolism
ATP from Cellular Respiration
Glycolysis – 2 ATP
Citric Acid Cycle – 2 ATP
E-Transport/Chemiosmosis – 34
ATP
–> Total ATP Produced = 38 ATP per Glucose
Molecule
Not Quite Perfect…
The maximum amount of ATP that can
be produced is 38, however, this value
may change due to other circumstances.
- Uncoupled proteins (H+ not powering
ATP synthase) - Using different electron shuttling
molecules may yield less ATP
Energy Efficiency
How efficient is aerobic respiration at
extracting the energy from glucose and
converting it to ATP?
Each ATP can produce 31 kJ/mol of energy
38 ATP X 31 kJ/mol = 1178 kJ/mol
Glucose contains 2870 kJ/mol
Efficiency = 1178 kJ/mol ÷ 2870 kJ/mol X 100 =
41%
Therefore 41% of the energy from Glucose is
converted into ATP
Energy Efficiency
41% doesn’t seem like a very
efficient system but in reality it is
much more efficient than many man
made machines (cars only utilize
around 25% of the energy from fuel)
The rest of the potential energy from
glucose is released as thermal energy
Metabolic Rate:
the amount of energy
that is expended per unit time in an organism
Basal Metabolic Rate (BMR)
The metabolic rate of an organism at rest
Varies from individual to individual
Higher fat content decreases BMR
Slows down as we age
Regulating Cellular Respiration
Your body needs to regulate cellular
processes to keep our metabolism
under control
Your body only needs a certain
amount of ATP to function properly
and so it must control its production
Negative Feedback Loops
When there is an excess amount of ATP
present then ATP can bind to phosphofructokinase (an enzyme in
glycolysis) to stop ATP production
Similarly Citrate (from the citric acid
cycle) can also inhibit
phosphofructokinase and prevent a build
up of unneeded molecules
Converting Food into Energy
We know Glucose can be converted into ATP
but what about Proteins, Complex
Carbohydrates and Fats?
Proteins
Converted into amino acids which can
be converted into pyruvate, acetyl CoA or
fumarate
Complex Carbs
Broken down into usable
glucose subunits
Fats
Can be converted into G3P (glycolysis) and
Acetyl CoA