10.1 Hormones: Chemical Regulators Flashcards
What is the endocrine system?
The endocrine system is a system of small
organs that involve the release of extracellular signalling molecules known as hormones.
What are Hormones?
Hormones are chemical regulators
produced by cells in one part of the body
that affect cells in another part of the
body.
Chemicals produced in glands and secreted
directly into the bloodstream are referred
to as
ENDOCRINE HORMONES
NON-TARGET HORMONES
Stimulate various parts of the body
TARGET HORMONES
Stimulate specific
sites of the body
NON-TARGET Examples
- Growth Hormone stimulates the
development of long bones - Insulin regulates blood sugar by increasing
permeability to glucose - Epinephrine (A.K.A Adrenaline) is produced
in times of stress
TARGET Examples
- Parathyroid hormone regulates calcium
levels in the body - Gastrin stimulates cells of the stomach to
produce digestive enzymes
Chemical Control Systems
The nervous system enables the body to
quickly adjust to environmental changes.
The endocrine system is designed to
maintain the body over longer periods of
time.
- For example growth hormone and various
sex hormones regulate and sustain the
body for many years.
Chemical Signals: Steroid and Protein
Hormones
Hormones can affect cells when they combine with
cell receptors.
Not all cells have the receptors for all hormones and
some cells have more receptors than
Steroid Hormones
- Diffuses through the cell membrane
- Attaches to a target receptor molecule
- The hormone-receptor complex moves
into nucleus and attaches to DNA - This activates a gene that sends a
message to the ribosomes in the
cytoplasm to create specific proteins.
Steroid Hormones =
Made from cholesterol (Lipidcompound) and includes male and female sex hormones and cortisol (stimulates the conversion
of amino acids to glucose by the liver)
- FAT SOLUBLE
Protein Hormone
- Hormone released from cell
- Hormone attaches to receptor site on cell
(Doesn’t diffuse across the membrane) - Hormone-receptor turns ATP into cyclic
AMP (Adenosine monophosphate) - Cyclic AMP acts as a messenger which
activates enzymes/directs protein
synthesis
Protein Hormones =
Obviously made from
proteins (Chains of amino acids). Includes insulin
and growth hormone.
- WATER SOLUBLE
Pituitary Gland
The pituitary gland exercises control over other endocrine glands and so may be considered the queen of the GLANDS!
The pituitary is connected to the hypothalamus.
The hypothalamus sends nerve signals to the
pituitary which stores and releases hormones.
The pituitary gland is made up of two lobes:
Posterior Lobe & Anterior Lobe