4.2 Molecular Genetics Flashcards
develop the one gene-one enzyme hypothesis
George Beadle and Edward Tatum (1934)
the process of making a working copy of an original
Transcription
proposes that a single gene has the genetic
information for making one enzyme. This is later changed to become the one gene - one polypeptide (protein) hypothesis; as enzymes are a type of polypeptide (protein).
one gene-one enzyme hypothesis
the making of a recyclable, workable copy of DNA but in the form of RNA
Transcription
the cell is turning nucleotide language (DNA/RNA) into amino acid language to make
proteins
Translation
the RNA language that will be translated into polypeptides.
Codon/Triplet Code
three nucleotide sequence of RNA
Codons
making of mRNA
mRNA Synthesis
Three Phases of Production
Initiation, Elongation, and Termination
Three phases of Translation
Initiation, Elongation, and Termination
Change in the nucleotide sequence of DNA or mRNA that code for a protein.
Mutation
Two major TYPES of Mutations
Point mutations, READING FRAMESHIFT
Point mutations
Silent, Missense, Nonsense Point Mutation
The whole DNA “sentence” is changed behind the mutation
READING FRAMESHIFT