406. Last few infections Flashcards

1
Q

How does botulism spread?

What is the mechanism of action of botulinum toxin

A

wound borne (IV drugs) or sausage (botulus)

blocks release of acetylcholine leading to flaccid paralysis

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2
Q

What are the signs of botulinum toxin?

A

Descending flaccid paralysis

botulinum toxin antitoxin

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3
Q

How do you treat tetanus?

A

ITU, anti-tetanus immunoglobulin,

wound debridement, metronidazole

diazepam for spasms

IV mag sulphate

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4
Q

How does rabies present?

A

HEache, myalgia odd behaviour, myalgia

Hydrophobia, aerophobia (fear of drafts/fresh air)

or paralysis–>coma–>death

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5
Q

What are the features of japanese tick enecphalitis?

A

Mild fever and headache

meningism,, altered mental status

Coma, seizures and spastic parlayis

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6
Q

What are the sympotms of west nile virus

A

Fever, headache, N&V

Lyphadenopathy

Neuroinvasive in 1%- leading to enecphalitis, meningitis and flaccid parlaysis

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7
Q

What is the highest cause of preventable epilepsy?

A

Neurocysticercosis- pork tapeworm disease

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8
Q

What is trachoma?

A

Infection endemic in africa caused by chlaymdia tachomatis. cuasing eye disease.

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9
Q

Describe the progression of trachoma?

A

Purulent discharge and follicular inflamamtion of the eylid

scarring,

eyelids turn inwards and irritate the cornea.

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10
Q

What is hitcheon’s sign with regards to herpes zoster virus?

A

Lesions at tip/side of node indicate V1 involvement and increased chance eye is involved

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11
Q

How does CMV retinitis present?

A

floaters, flashing lights

eye pain

visual loss

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12
Q

How does occular toxoplasmosis present?

A

Posterior uveitis

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13
Q

What causes river blindess?

A

Ochocerca volvulus- wom transmitted by the bite of black flies leading to adult larvae produced at mite and releasing 1000 of babies a day

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14
Q

What are the symtoms of river blindness?

A

Skin disease
Eye disease
Lymph damage

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15
Q

What is scabies

What are the symptoms

A

Mite that burrow into skin, cuasing allergic reaction

Rash, itching,

Secondary bacterial infection

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16
Q

What is the treatment for scabies?

A

Topical permethrin or malathion

17
Q

What are the symtpoms of leishmaniasis?

A

Sand fly bite leads to

Itchy papule leading to painless ulcer

18
Q

What is myasis?

What is the teatment

A

Painful swelling that indicates larvae infection under skin. Mobile feels riggly

Petrol prok fat causes asphyxiation

19
Q

What are the presenting signs of leprosy?

A

Hypopigmented lesions

Sensory loss

Thickened nerves

Nodules plaques, epistaxis

Eye disease

20
Q

What organism causes malaria?

How is malaria treated?

A

Rifampcin
Dapsone
Clofazimine

21
Q

What is yaws

A

Chronic granulmatous diease casued by treponema pertenue

Presents with pallpiloma and dactilysis

22
Q

How is Yaws treated?

A

Azithromycin