4. DOGS: Brucellosis (Brucella canis) B.CANIS Flashcards

BRUSELLOOSI

1
Q

disease

A

-contagious disease of dogs

-brucellosis

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2
Q

caused by

A

Brucella canis

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3
Q

characterized by

A

reproductive failure

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4
Q

agent

A

-agent: Brucella canis (BRUCELLA CANIS)

-gram -

-facultatively intracellular

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5
Q

other Brucella species that can affect dogs (3)

A
  1. B.abortus
  2. B. melitensis
  3. B. suis
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6
Q

can remain viable

A

for months in conditions of high humidity, low temperatures and no sunlight

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7
Q

readily killed by

A

most commonly available disinfectants

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8
Q

HR

A

dogs

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9
Q

zoonotic?

A

YES !!!!

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10
Q

affects

A

sexually mature canines, no gender predisposition (molemmat sukupuolet)

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11
Q

more common in

A

stray/feral dogs (=kodittomat ja villiintyneet koirat

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12
Q

where

A

worldwide distribution

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13
Q

risk factors

A

housing or breeding with infected animals

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14
Q

death is

A

rare

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15
Q

most affected by death

A

fetuses and neonates

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16
Q

transmission: excretion

A

-vaginal discharge (following abortion)

-urine

-milk

-semen

-prostatic fluid

-vaginal fluid durin estrus

-lochia (signs) of parturition

17
Q

ways of transmission

A

-direct contact

-venereal

-fomites

-in utero

18
Q

transmission: route

A

-alimentary (ingestion)

or

  • through MM

> oral cavity
conjunctiva
nasal tissue
penis or vaginal vault (emätin)

19
Q

IP

20
Q

CS: female

A

-failure to conceive

-abortion at 45-55 days of gestation, possible with no other signs

-birth of stillborn, partially autolyzed, or weak pups

-persistent, highly infective mucopurulent or serosanguineous vulvar discharge for 1-6 weeks of postpartum (limapurskuttelu tai verta sisältävä vuoto)

-placentitis and metritis (istukan tulehdus, kohtutulehdus)

21
Q

CS: male

A

-scrotal swelling

-decreased libido

-back pain

-testicular atrophy (chronic infections)

-poor semen quality

-epididymal inflammation

22
Q

CS: EITHER GENDER

A

-lymphadenopathy

-signs of recurrent uveitis (toistuva silmätulehdus)

-lameness

-paraspinal pain with paresis or paralysis

23
Q

PM

A

-LYMPH NODE ENLARGEMENT: >retropharyngeal, inguinal LNs
>generalized lymphadenitis

-splenomegaly=suurentunut perna- enlarged spleen

-hepatomegaly=suurentunut maksa

> males:
-scrotal dermatitis, epididymitis, scrotal edema, scrotal edema, orchitis, prostatitis, testicular atrophy and fibrosis

> females:
-metritis, vaginal discharge

> aborted puppies:
-partially autolyzed and have evidence of generalized bacterial infection

24
Q

DDx

A

-abortion:
>B.abortus, B.suis, B.melitensis, salmonella spp, campylobacter spp., E-coli or streptococcus spp., canine herpesvirus, canine distemper or canine adenovirus, mycoplasmas, toxoplasma gondii, progesterone deficiency, hypothyroidism

-infertility/poor semen quality/azoospermia(miehen siemennesteessä ei siittiöitä):
>improper timing for breeding, subclinical uterine infection, testicular or prostatic dz

-scrotal enlargement: >orchitis(kivekset tulehtuneet), epididymitis, torsion of spermatic cord, hernia, testicular neoplasia, abscess, variocele(suonikohjuja kivespussiin), hydrocele (kivespussissa nestettä), hematoma (verta kertyy kudoksiin)

25
diagnosis: material
-blood -tissue samples: LNs, bone marrow, placenta, eye, fetus -fluids: >semen >lochia (lapsivuoto, emättimestä nestettä) >urine >milk
26
diagnosis: in the lab
-serology (AGID, ELISA) >will identify positive dog FROM 8-12 week post infection UNTIL 3-4 years after achieving bacteremia -bacterial culture: definitive!!!! LUOTETTA >positive cultures occur 2-4 weeks post infection -PCR
27
Tx
-ABs may be useful! >combination of 2, long term ABs >no Tx is certain to eliminate B.canis >recrudescence (uusiutuminen) is possible, especially when stressed > euthanasia recommended
28
vaccine
NO
29
prevention
-kennels and breeding programs >remove infected dogs >individual caging >repeated testing -neuter -wear gloves