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animal inf.diseases 2-part 3 > 3. CATS: Feline infectious peritonitis-FIP (FELINE CORONAVIRUS FCoV) > Flashcards

3. CATS: Feline infectious peritonitis-FIP (FELINE CORONAVIRUS FCoV) Flashcards

TARTTUVA VATSAKALVONTULEHDUS

1
Q

disease

A

-contagious disease of felines

-feline infectious peritonitis (FIP)

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2
Q

caused by

A

feline coronavirus

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3
Q

characterized by

A

-body cavity effusions(=kehon onteloon kertyy nestettä)

OR

-neurological signs

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4
Q

agent, family, serotypes

A

-agent: Feline coronavirus (FCoV)

> family: Coronaviridae

> 2 serotypes : 1 and 2
EU and USA mainly serotype 1
Japan mainly serotype 2

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5
Q

related to

A

-TGE virus in pigs, canine and human coronaviruses

-TGEV= transmissible gastroenteritis virus

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6
Q

largest known

A

RNA

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7
Q

susceptible

A

highly susceptible to mutation

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8
Q

FIP virus is mutation of

A

benign FCoV

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9
Q

survival

A

-does not survive in environment for long
>less 48h

> in dry environment less 6 weeks

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10
Q

readily inactivated by

A

most common disinfectants

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11
Q

HR

A

felines

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12
Q

most widespread infectious disease of

A

cats

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13
Q

mostly

A

sporadic disease

=satunnaisesti ja epäsäännöllisesti populaatiossa

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14
Q

most susceptible

A

-young cats during post weaning periods

> peak age: 6 months to 2 years

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15
Q

more in

A

males than females

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16
Q

purebred cats: asian breeds: Birman, Himalayan

A

are most susceptible

17
Q

risk factors

A

-stress, multicat households

> FCoV widespread or even ubiquitous in multicat environments

=erittäin yleinen tai laajalle levinnyt monien kissojen populaatioissa ja ympäristöissä

18
Q

morbidity

A

-90% of cats have antibodies, but only 5% develop clinical dz

19
Q

mortality

A

95%!!

20
Q

transmission: excretion

A

-FECES

-saliva

-urine

-respiraotry secretions

21
Q

ways of transmission

A

-direct contact

-fomites (litter box)

22
Q

transmission route

A

-fecal-oral

-oronasal

or

-through saliva (e.g mutual grooming)

23
Q

forms (2)

A

-Wet form = Effusive

-Dry form = Noneffusive (OCULAR abnormalities)

24
Q

nonspecific clinical signs

A

-lethargy

-inappetence

-weight loss

25
Q

CS: EFFUSIVE (wet) form

A

-abdominal distention with palpable fluid wave

-dyspnea, muffled heart sounds and muffled lung sounds
>due to pleural effusion

-also there might be palpable abdominal masses

=neste kertyy=effusive

26
Q

CS: NONEFFUSIVE (dry) form

(OCULAR)

A

-ocular abnormalities-change in iris color due to iritis/uveitis, hyphen, aqueous flare, keratin precipitates, vitreous clouding, vascular cuffing

-icterus

-palpable abdominal mass(es)-organomegaly
> e.g. enlarged mesenteric LNs, nodules in other organs, intestinal thickening

-raised intradermal pustules (non-rustic cutaneous lesions)

=noneffusive=neste ei kery (kuiva)

27
Q

CS: neurologic signs

A

-ataxia

-incoordination

-paresis (lihasheikkous)

28
Q

DDx

A

-neoplasia (lymphoma)

-lymphocytic/nonsuppurative cholangitis

-pyothorax/cyclothorax = märkää rintaontelossa tai keuhkopussin sisällä on ontelo tai kysta

-congestive heart failure

-ocular changes: toxoplasmosis, FIV (feline immunodeficiency virus ), FeLV , systemic mycosis

-hyperglobulinemia: lymphoma, multiple myeloma, chronic infection

29
Q

diagnosis: material

A

-blood

-effusion (peritoneal) fluid

-samples from affected tissues

30
Q

diagnosis in lab

A

-RIVALTA TEST:
>8ml distilled water + 1 drop of 98% vinegar + 1 drop of effusion fluid
>if drop disappears = negative
>if drop stays = positive

-PCR

-Histopathology

-Serology :
>positive titers only represents exposure to FCoV, not specially FIP!
> titers 1:16000 suggestive to FIP in cats showing signs of dz

31
Q

most cats with positive serologic titers

A

never develop FIP

32
Q

Tx

A

-no

-provide comfort and supportive / palliative care

33
Q

Tx: acute Tx

A

-thoracocentesis

-oxygen therapy

-IV fluids

34
Q

TX: chronic Tx

A

-antiviral drugs

-immunomodulating drugs

-immune suppression drugs

35
Q

cats with effusive form generally

A

die within 2 months of onset of CS

36
Q

cats with noneffusive(DRY, OCULAR) form tend to have more

A

chronic dz course that is also generally FATAL

37
Q

prevention

A

-vaccination

-optimize husbandary practices
> in catteries : separate seronegative cats from seropositive
> in catteries : remove kittens from positive queens and other adult cats at 5-6 week old
> when possible, only seronegative cats should be added to cattery

38
Q

most cats with positive serologic titers

A

NEVER DEVELOP FIP

39
Q

stays in

A

macrophages

animal inf.diseases 2-part 3 (20 decks)

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