3.8 Obese Metabolism Flashcards
Weight gain or weight loss affects adipose cells how?
Affects the size but not the number of cells
Individuals with upper or lower body fat have greater health risks
Upper body fat has greater health risks than pear fat
T or F, Obesity is a disease of chronic inflammation
True
What is the product of the ob gene
Leptin
How much of leptin is released in the body?
In proportion to mass of tissue
What two things occur during a secretion of leptin
Decrease in apetite
Increase in energy expenditure
Signals of feeding whether stimulatory or inhibitory are integrated and relayed in what portion of the CNS
Hypothalamus
Overeating and obesity are associated with damage to what two things?
Ventromedial Nucleus
Paraventricular Nucleus
Weight loss and Anorexia related to what region of CNS?
Lateral Hypothalamic regions
Weight is regulated by a balance between stimulation and inhibition of what two types of neurons in the hypothalamus
Orexigenic
Anorexigenic
Orexigenic neurons stimulate what?
Eating and inactivity
Anorexigenic neurons function?
They suppress eating
What two things are released by orexigenic neurons of the hypothalamus
NPY (nucleotide Y)
AgRP (Agouti related protein)
Anorexigenic neurons release what two things?
POMC (Pro-Opiomelanocortin)
CART (Cocaine and Amphetamine regulated Transcript)
Leptin reduces what and stimulates what?
Reduces fuel intake
Stimulates energy expenditure
