1.7 Carbohydrate Structure and Digestion Flashcards

0
Q

Two epimers of D-Glucose

A

D-Mannose (epimer at C-2)

D-Galactose (epimer at C-4)

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1
Q

3 main categories of Carbohydrates

A
  1. Monosaccharides
  2. Oligosaccharides
  3. Polysaccharides
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2
Q

In the Hemi acetal (cyclic structure) what parts of the carbohydrate bond to each other to become cyclic

A

Carbonyl group covalently bonds to OH group

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3
Q

T or F, The cyclic structure of Carbohydrates are more stable than open chain structure

A

True

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4
Q

Pyranose has how many carbons involved in the ring?

A

6 membered ring

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5
Q

Which is the less prevalent cyclic structure?

A

Furanose (5 membered rings)

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6
Q

alpha linkages on anomeric carbon has the OH below or above the plane

A

Below

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7
Q

Which anomeric linkage has the OH above the plane?

A

beta linkage

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8
Q

What is a glycoside

A

It is technically a disaccharide. It is formed when OH group attached on an Anomeric carbon condenses with a group on another monosaccharide

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9
Q

What type of linkages are involved with Starch?

A

alpha-1,4 and alpha-1,6.

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10
Q

Cellulose has what type of linkages?

A

beta-1,4 linkages.

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11
Q

Is Cellulose branched or unbranched

A

Unbranched

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12
Q

What are the linkages of Glycogen

A

alpha-1,4 and alpha-1,6. Highly branched!

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13
Q

What sugars are found in starch

A

Amylose (alpha-1,4) and Amylopectin (alpha-1,6)

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14
Q

Where is Salivary Amylase found?

A

In the mouth

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15
Q

What does Salivary Amylase digest?

A

alpha-1,4 linkages

16
Q

What enzyme of digestion is found in the lumen of small intestine

A

Pancreatic Amylase

17
Q

What are the digestion products of starch after it has been broken down by amylase?

A

Dextrins, Maltose, Isomaltose

18
Q

Name the brush border enzymes

A

Sucrase
Lactase
Maltase
Isomaltase

19
Q

Purpose of Brush border enzymes

A

Break down disaccharides to monosaccharides

20
Q

4 functions of Cellulose

A
  1. Increase stool volume
  2. Increase stool softness
  3. Decrease transit time
  4. Increase Satiety
21
Q

Two results of undigested carbohydrates (disaccharides?) passing into large intestine

A
  1. Osmotic Diarrhea

2. Bacterial fermentation of carbs to 2 & 3 carbon fragments plus CO2 and H2 gas

22
Q

Sucrose is made up of what two sugars?

A

Glucose and Fructose

23
Q

Lactose is made up of what two sugars

A

Glucose and Galactose

24
Q

What sugars make up Cellulose

A

Glucose with beta-1,4 linkages

25
Q

Maltose sugars?

A

Glucose (alpha-1,4 linkages)

26
Q

Outline the association between oral bacteria, sucrose (carbs) and tooth decay

A
  1. S. Mutans can cleave Sucrose into Fructose & Glucose
  2. Fructose is used by the bacteria as a source of anaerobic energy
  3. Glucose is polymerized into Dextran which helps attach bacteria to tooth enamel.
  4. Dextran can be broken down into glucose producing lactic acid and tooth decay
27
Q

What is the most common disaccharidase deficiency

A

Lactase, Lactose intolerance