3.3 Water Soluble Vitamins Flashcards
Thiamine is a coenzyme in what situations?
Decarboxylations of alpha keto acids such as pyruvate
B1 refers to what vitamin?
Thiamine
What deficiency is involved in Thiamine deficiency?
Beri Beri
What deficiency is found in alcoholics and is characterized by a loss of memory. This is also a deficiency of Thiamine.
Wernick-Korsakoff Syndrome
How is Riboflavin used in metabolism?
As FAD, It is used in metabolic pathways
Riboflavin is also called what?
Vitamin B2
Vitamin B3 is also called?
Niacine
What vitamin is used in the metabolism as NAD+ and NADP
Niacine (B3)
Niacine deficiency is connected to what disorder?
Pellagra (3 D’s –> Dermatitis, Diarrhea, Dementia)
What are the 3 D’s of Pellagra?
Dermatitis, Diarrhea and Dementia
Other name for Vitamin B5
Pantothenate
What is Vitamin B5 (Pantothenate) used for in metabolism?
Synthesis of Coenzyme CoA
What vitamin is Pyrodoxine?
Vitamin B6
What vitamin is used in the metabolsim as a coenzyme for decarboxylases and aminotransferase (transaminase) reactions?
Pyrodoxine (B6)
What vitamin is required for Heme synthetic pathway?
Pyrodoxine (B6)
Biotin (B7) has what important role in metabolism?
Coenzyme in CO2 fixation in carboxylation reactions
What is avidin and how is involved with Vitamin B7?
Avidin is an egg white protein that forms with biotin so that biotin cannot properly perform its function
Another name for Vitamin B7
Biotin
Folic Acid is involved in what 2 important parts of metabolism?
One Carbon Metabolism
Essential for Purine and Pyrimidine Synthesis
What is a major disease occurring from a Folic Acid deficiency
Megoblastic Anemia
Vitamin B12 is also called what?
Cobalamin
How is Vitamin B12 (Cobalamin) used in metabolism
Required in synthesis of Methionine and Isomerization of methylmalonyl CoA
What occurs during a B12 deficiency?
Methyl form of Tetrahydrofolate (N5 methyl) accumulates and cannot be used to help form Methionine.
What two vitamins are involved in megoblastic anemia?
Folic Acid
Cobalamin (B12)
Vitamin C is also called?
Ascorbic Acid
What vitamin is involved in metabolism as a coenzyme in hydroxylation reactions
Vitamin C (Ascorbic Acid)
A deficiency in Vitamin C is characterized by what?
Defective formation of collagen fibers of CT
Vitamin C deficiency is largely connected what what disease?
Scurvy - bleeding into skin, bleeding gums
