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Metabolism > 3.3 Water Soluble Vitamins > Flashcards

3.3 Water Soluble Vitamins Flashcards

0
Q

Thiamine is a coenzyme in what situations?

A

Decarboxylations of alpha keto acids such as pyruvate

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1
Q

B1 refers to what vitamin?

A

Thiamine

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2
Q

What deficiency is involved in Thiamine deficiency?

A

Beri Beri

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3
Q

What deficiency is found in alcoholics and is characterized by a loss of memory. This is also a deficiency of Thiamine.

A

Wernick-Korsakoff Syndrome

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4
Q

How is Riboflavin used in metabolism?

A

As FAD, It is used in metabolic pathways

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5
Q

Riboflavin is also called what?

A

Vitamin B2

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6
Q

Vitamin B3 is also called?

A

Niacine

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7
Q

What vitamin is used in the metabolism as NAD+ and NADP

A

Niacine (B3)

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8
Q

Niacine deficiency is connected to what disorder?

A

Pellagra (3 D’s –> Dermatitis, Diarrhea, Dementia)

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9
Q

What are the 3 D’s of Pellagra?

A

Dermatitis, Diarrhea and Dementia

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10
Q

Other name for Vitamin B5

A

Pantothenate

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11
Q

What is Vitamin B5 (Pantothenate) used for in metabolism?

A

Synthesis of Coenzyme CoA

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12
Q

What vitamin is Pyrodoxine?

A

Vitamin B6

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13
Q

What vitamin is used in the metabolsim as a coenzyme for decarboxylases and aminotransferase (transaminase) reactions?

A

Pyrodoxine (B6)

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14
Q

What vitamin is required for Heme synthetic pathway?

A

Pyrodoxine (B6)

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15
Q

Biotin (B7) has what important role in metabolism?

A

Coenzyme in CO2 fixation in carboxylation reactions

16
Q

What is avidin and how is involved with Vitamin B7?

A

Avidin is an egg white protein that forms with biotin so that biotin cannot properly perform its function

17
Q

Another name for Vitamin B7

A

Biotin

18
Q

Folic Acid is involved in what 2 important parts of metabolism?

A

One Carbon Metabolism

Essential for Purine and Pyrimidine Synthesis

19
Q

What is a major disease occurring from a Folic Acid deficiency

A

Megoblastic Anemia

20
Q

Vitamin B12 is also called what?

A

Cobalamin

21
Q

How is Vitamin B12 (Cobalamin) used in metabolism

A

Required in synthesis of Methionine and Isomerization of methylmalonyl CoA

22
Q

What occurs during a B12 deficiency?

A

Methyl form of Tetrahydrofolate (N5 methyl) accumulates and cannot be used to help form Methionine.

23
Q

What two vitamins are involved in megoblastic anemia?

A

Folic Acid

Cobalamin (B12)

24
Q

Vitamin C is also called?

A

Ascorbic Acid

25
Q

What vitamin is involved in metabolism as a coenzyme in hydroxylation reactions

A

Vitamin C (Ascorbic Acid)

26
Q

A deficiency in Vitamin C is characterized by what?

A

Defective formation of collagen fibers of CT

27
Q

Vitamin C deficiency is largely connected what what disease?

A

Scurvy - bleeding into skin, bleeding gums

Metabolism (31 decks)

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