3.2 Fed State Flashcards
During prolonged starvation, the brain uses what as a fuel?
Ketone bodies produced by the liver. Beware that ketone bodies only partly replace glucose as the fuel during this time
What is the main fuel for the brain
Glucose
The brain consumes about how many grams of glucose a day?
120 grams
What percent of the bodies glucose is utilized by the brain?
60%
What are the major fuels for the Muscle in general
Glucose
Fatty Acids
Ketone Bodies
What is the major fuel source of the muscle at rest
Fatty acids meeting 85% of energy needs
Where is the major site of Fatty Acid Synthesis?
Liver
Fatty Acid synthesis can occur in the adipose tissue under what conditions?
Fed State when there is ample supply of Glucose
What is the major purpose of the Kidney?
To produce Urine and excrete metabolic wastes
What occurs in the liver during starvation?
Becomes an important site of gluconeogenesis and may contribute as much as half of the blood glucose
Liver removes how much of blood glucose?
As much as 2/3 of glucose from the blood
Most of the glucose taken up by the liver is converted into what?
Glycogen
What are the 4 major gluconeogenic precursors used in the liver to produce glucose?
Lactate and Alanine (muscle)
Glycerol (Adipose tissue)
Glucogenic Amino Acids (from diet)
What are the two main pathways that the liver uses to produce glucose in times of need?
Glycogenolysis
Gluconeogenesis
What occurs to FA in the liver when there are abundant fuels available?
They are esterified and secreted in blood as VLDL
