308 Drug discovery and development (lecture 1-3)

Question 1

What happens in the pre-clinical phase of drug development?

Answer 1

Drugs undergo laboratory and animal testing to answer basic questions about safety

1.Choose disease
2.Choose a drug target (High-throughput screening)
Identify a bioassay
4.Find a lead compound
5.Isolation, purification, structural determination

Question 2

What happens in the clinical phase of drug development?

Answer 2

Clinical trials and volunteer studies to finetune the drug for human use

Aimed at safety and efficacy of the drug