30. Drugs used in coagulation disorders II: Anticoagulant drugs Flashcards

1
Q

Which are the 2 big groups of anticoagulant drugs?

A
  • Binding and inactivation of coagulation factors:
    • Part of an inactivation complex
    • Direct thrombin inhibition
    • Direct Xa inhibition
  • Inhibition of the coagulation factor synthesis
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2
Q

Which are the anticoagulants part of an inactivation complex?

A
  • Heparin
    • ​UFH
    • LMWH
  • Fondaparinux
  • Danaparoid
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3
Q

Which are the anticoagulants that directly inhibit thrombin?

A
  • Hirudin
  • Bivalirudin
  • Argatroban
  • Dabigatran etexilate
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4
Q

Which are the anticoagulants that inhibit directly Xa?

A
  • Rivaroxaban
  • Apixaban
  • Edoxaban
  • Betrixaban
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5
Q

Which are the anticoagulants that inhibit coagulation factor synthesis?

A

Coumarins:

  • Warfarin
  • Acenocoumarol
  • Phenprocoumon
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