21. Antiarrhythmic agents

Question 1

Which are the groups of antiarrhythmic drugs?

Answer 1

• Class I - Na⁺ channel blockers
  
  • Ia - intermediate dissociation
  • Ib - fast dissociation
  • Ic - slow dissociation
• Class II - beta blockers
• Class III - K⁺ channel blockers
• Class IV - Ca²⁺ channel blockers
• Others

Question 2

Which are the class Ia drugs?

Answer 2

Na⁺ channel blockers - Medium dissociation:

• Quinidine
• Procainamide
• Disopyramide
• (Prajmaline)

Question 3

Which are the class Ib drugs?

Answer 3

Na⁺ channel blockers - Fast dissociation:

• Lidocaine
• Mexiletine
• (Phenytoin)

Question 4

Which are the class Ic drugs?

Answer 4

Na⁺ channel blockers - Slow dissociation:

• Flecainide
• Propafenone

Question 5

Which are the class II drugs?

Answer 5

Beta blockers:

• Metoprolol
• Propanolol
• Esmolol
• Sotalol

Question 6

Which are the class III drugs?

Answer 6

K⁺ channel blockers:

• Amiodarone
• Dronedarone
• Sotalol
• Dofetilide
• (Ibutilide)
• Vernakalant
• (Bretylium)

Question 7

Which are the class IV drugs?

Answer 7

Ca²⁺ channel blockers:

• Verapamil
• Diltiazem

Question 8

Which are the other drugs?

Answer 8

• Adenosine
• Mg-sulphate
• Digoxin