3-10 Flashcards
Any substance that affects our bodies and minds
drug
Does substance include alcohol, tobacco, and caffeine?
yes
a temporary state of poor judgment, mood changes, irritability, slurred speech, and poor coordination
INTOXICATION
consists of perceptual distortions and hallucinations
HALLUCINOSIS
Example of a substance that produces hallucinosis
LSD
Pattern of maladaptive behaviors and reactions brought about by repeated use of substances
SUBSTANCE USE DISORDER
People sometimes become physically dependent on the substances, developing a __________for it and experiencing __________
TOLERANCE, WITHDRAWAL
The brain and body’s need for ever larger doses of a drug to produce earlier effects
TOLERANCE
Unpleasant, sometimes dangerous, reactions that may occur when people who use a drug regularly stop taking or reduce their dosage of the drug
WITHDRAWAL
Four categories of substances used and studied
depressants, stimulants, hallucinogens, cannabis
Methods of availability of drugs in our society
Harvested from nature; derived from natural substances; produced in laboratory; Require a physician’s prescription; legally available to adults; some illegal under all circumstances
Category of substance that may slow the activity of the CNS, Reduce tension and inhibitions, May interfere with judgment, motor activity, and concentration
Depressants
Three most widely used depressants
alcohol, sedative-hypnotics, opioids
Active ingredient in alcoholic beverages
ethyl alcohol
Ethyl alcohol is absorbed where and effects what
stomach lining; CNS
Ethyl alcohol help what neurotransmitter shut down neurons and relax the drinker
GABA
Levels of impairment are tied to what acronym
Blood Alcohol Concentration (BAC)
A given amount of alcohol has a lesser effect on a ______ person than a _______ one
large, small
an enzyme in the stomach that metabolizes alcohol before it enters the blood
DEHYDROGENASE
Women have less of what enzyme and become more intoxicated than men on equal doses of alcohol
alcohol DEHYDROGENASE
BAC associated with relaxation and comfort
BAC 0.06
BAC associated with intoxication
BAC 0.09
BAC associated with death
0.55
Organ where alcohol is metabolized
liver
Rate at which liver metabolizes alcohol
0.25oz/hr, can’t speed up
First brain area effected by alcohol
judgment and inhibition
Second brain area effected by alcohol
less ability to make judgments, speak clearly, remember well
Third brain area effected by alcohol
increased motor difficulties, reaction time slows
In general, people with alcohol use disorder do what three things
(1) Drink large amounts regularly, (2) Rely on it to enable them to do things that would otherwise make them anxious, (3) Eventually find drinking interferes with social behavior and the ability to think and work
Levels of impairment are closely related to the concentration of
ethyl alcohol in the blood
Most of the alcohol is broken down, or metabolized, by the liver into
carbon dioxide and water, which can be exhaled and excreted
The average rate of this metabolism is
25 percent of an ounce per hour, but different people’s livers work at different speeds; thus rates of “sobering up” vary
Type of drinking that is a serious problem on college campuses
Binge drinking
Increased tolerance of alcohol requires what to feel its effects
greater amounts
Withdrawal symptoms sometimes experienced at cessation of drinking
nausea and vomiting
A dramatic withdrawal reaction experienced by some people with alcoholism. It consists of confusion, clouded consciousness, and terrifying visual hallucinations
DELIRIUM TREMENS (DTs)
Demographics of DTs
men > women, some teenagers
Three ways alcohol can damage people
physical health, nutritional, fetal alcohol syndrome
Term for physical health liver damage due to alcohol
cirrhosis
A nutrition problem alcohol-related disorder marked by extreme confusion, memory impairment, and other neurological symptoms
Korsakoff’s syndrome
A cluster of problems in a child, including low birth weigh and irregularities in the head
Fetal alcohol syndrome
A class of drug used in low doses to reduce anxiety and in higher doses to help people sleep. Also called an anxiolytic drug
SEDATIVE-HYPNOTIC (ANXIOLYTIC) DRUGS
Two examples of SEDATIVE-HYPNOTIC (ANXIOLYTIC) DRUGS
BARBITURATES, BENZODIAZEPINES
Addictive sedative-hypnotic drugs that reduce anxiety and help people sleep
Barbiturates
At low doses, ___________ are similar in effect to alcohol by attaching to GABA receptors, but at high doses, they slow breathing and are lethal
barbiturates
Repeated use of barbiturates can quickly result in
sedative-hypnotic use disorder
A great danger of barbiturate tolerance is that the _________________, even while the body is building a tolerance for the sedative effects
lethal dose of the drug remains the same
Barbiturates have largely been replaced with
Benzodiazepines
Benzodiazepine withdrawal is particularly dangerous because it can cause
convulsions
Three common benzos
Xanax, Ativan, and Valium
Have depressant effect on the CNS by binding to GABA receptors and increasing GABA activity
Benzodiazepines
Relieve anxiety without causing drowsiness, less likely to slow breathing and lead to death by overdose, Can cause intoxication and lead to addiction
Benzodiazepines
Opium or any of the drugs derived from opium, including morphine, heroin, and codeine
Opioid
A highly addictive substance made from the sap of the opium poppy
Opium
Term for both natural and synthetic opioids
narcotics
Most common method of narcotics use, although other techniques have been increasing in recent years
Injection