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Farma 2P > 2.7 Glucocorticoides > Flashcards

2.7 Glucocorticoides Flashcards

1
Q

Glucocorticoides acción corta:

A

Cortisona
Hidrocortisona

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2
Q

Uso glucocorticoides de acción corta:

A

Insuficiencia suprarrenal aguda
Insuficiencia suprarrenal primaria y secundaria

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3
Q

VA cortisona

A

Oral

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4
Q

Metabolito cortisona

A

Hidrocortisona

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5
Q

Adyuvante norepinefrina en shock séptico

A

Cortisona

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6
Q

Glucocorticoides acción media:

A

Fludrocortisona
Triamcinolona
Prednisona
Prednisolona
Metilprednisolona

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7
Q

Triamcinolona usos:

A

Artritis reumatoide (intraarticular)

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8
Q

Prednisona VA

A

Oral

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9
Q

Glucocorticoide #1 profilaxis rechazo trasplante

A

Prednisona

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10
Q

Glucocorticoide #1 para uso en embarazadas

A

Prednisona

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11
Q

Metabolito de prednisona

A

Prednisolona

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12
Q

Glucocorticoide de acción media #1 en hepatopatas

A

Prednisolona

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13
Q

EA prednisolona

A

Sabor muy amargo

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14
Q

Uso prednisolona

A

IV tendinitis, bursitis, osteoartritis

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15
Q

Glucocorticoide que se usa para tx de shock medular

A

Metilprednisolona

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16
Q

Metilprednisolona usos

A

Shock medular
Exacerbación enfermedad reumatica (MS)
Asma
Sd nefrótico

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17
Q

EA metilprednisolona

A

Sordera súbita

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18
Q

Glucocorticoides de acción prolongada:

A

Betametasona
Dexametasona

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19
Q

Administración IM 48 hrs previas al parto para ayudar a la maduración pulmonar del feto (<36 semanas)

A

Betametasona

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20
Q

Betametasona es de acción

A

Prolongada

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21
Q

Prednisona es de acción:

A

Media

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22
Q

Triamcinolona es de acción:

A

Media

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23
Q

Dexametasona es de acción:

A

Prolongada

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24
Q

EA dexametasona:

A

Cataratas, glaucoma

25
Q

Glucocorticoide usado para el dx de Sd de Cushing

A

Dexametasona

26
Q

Dexametasona CI

A

Embarazadas

27
Q

Glucocorticoide de acción prolongada más potente para retener Na

A

Fludrocortisona

28
Q

Usos fludrocortisona

A

Aldosteronismo
Sincope neurocardiogénico
Restitución de mineralocorticoides

29
Q

EA fludrocortisona:

A

Edema, hipokalemia

30
Q

Glucocorticoides inhalados:

A

Fluticasona
Budesonida
CIclesonida
Flunisonida
Beclometasona

31
Q

Fluticasona indicaciones:

A

Pedia
Con salmeterol para tx de asma/epoc grave

32
Q

Budesonida indicaciones:

A

Rinitis alérgica en niños < 8 años
Crohn
Colitis ulcerativa

33
Q

Ciclesonida indicaciones:

A

Asma en > 12 años

34
Q

Beclometasona indicaciones:

A

Asma en niños > 6 años
Rinitis alérgica en > 12 años
Pólipos

35
Q

Pasireotida MDA

A

Afinidad a SSTR5 que inhibe ACTH

36
Q

Pasireotida usos

A

Cushing inoperable
Bajar cortisol en px con tumor secretor de ACTH

37
Q

EA pasireotida

A

Hiperglucemia, cálculos

38
Q

Cabergolina MDA

A

Agonista D2

39
Q

Cabergolina usos

A

Hiperprolactinemia

40
Q

Hiperprolactinemia das

A

Cabergolina

41
Q

Ketoconazol MDA

A

Antimicotico, inhibe síntesis esteroides.
Inhibe: colesterol desmolasa, 17 alfa hidroxilasa y 17,20 liasa

42
Q

EA ketoconazol

A

Hepatotóxico, teratógeno, sedante, disminuye libido, nausea y vómito

43
Q

Metirapona MDA

A

Inhibe síntesis II beta hidroxilasa

44
Q

Fx para embarazada con Cushing

A

Metirapona

45
Q

Metirapona usos:

A

Embarazadas con cushing
Pruebas función suprarrenal

46
Q

EA metirapona

A

Edema, hirsutismo, HTA

47
Q

Etomidato MDA

A

Inhibe síntesis II beta hidroxilasa
Agonista GABA

48
Q

Único tx IV para cushing

A

Etomidato

49
Q

EA etomidato

A

Insuficiencia suprarrenal

50
Q

VA etomidato

A

IV

51
Q

Citotóxico que bloquea colesterol desmolasa, 17 hidroxicorticoesteroide

A

Mitotano/ prilostano

52
Q

Usos mitotano/ prilostano

A

Adenoma/ carcinoma suprarrenal inoperable

53
Q

MDA aminoglutetimida

A

Inhibe colesterol desmolasa

54
Q

EA aminoglutetimida

A

Rash, visión borrosa, sedación

55
Q

Mifepristona MDA

A

Antagonista del receptor de progesterona

56
Q

Usos mifepristona

A

Abortivo 1er trimestre
Induce parto (muerte fetal)
Como next day pero se prefiere ulipristal)

57
Q

EA mifepristona

A

Si aumentas dosis aumentan niveles ACTH y cortisol

58
Q

Glucocorticoides tópicos:

A

Hidrocortisona
Betametasona
Prednisolona (gotas oftálmicas)
Clobetasol

Farma 2P (16 decks)

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