2.2 Nucleic Acids Flashcards

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1
Q

What are the two types of nucleic acid?

A

DNA- deoxyribose nucleic acid

RNA- ribose nucleic acid

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2
Q

What are nucleotides?

A

Monomer units making up nucleic acids (polymer)

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3
Q

What are nucleotides made up of?

A
  • carbon
  • hydrogen
  • oxygen
  • nitrogen
  • phosphorus
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4
Q

What are the 3 components of a nucleotide?

A
  • phosphate group
  • a sugar
  • a base
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5
Q

What are nucleic acids?

A

Biochemical macromolecules involved with the transmission of inherited information

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6
Q

What are the two types of nucleotide bases?

A
  • purines

* pyramidines

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7
Q

What base is the biggest?

A

Purines

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8
Q

What are purines and what are the two purines?

A

Double ringed structures that always pair up with pyramidines
• adenine
• guanine

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9
Q

What are pyramidines and what are the two types?

A

Single ringed structures that always pair up with purines
• thymine
• cytosine
• uracil (only found in RNA)

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10
Q

How do purines bond to pyramidines?

A

By hydrogen bonds

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11
Q

What reaction occurs to form a nucleotide?

A

A condensation reaction as two water molecules are lost

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12
Q

How is a nucleotide formed?

A

A nucleotide is formed when a phosphoric acid and a base are chemically bonded to a sugar molecule

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13
Q

When is water given off?

A

When the phosphate group and base groups are joined

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14
Q

When is a polynucleotide formed?

A

When many nucleotides join

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15
Q

When is a dinucleotide formed?

A

When 2 nucleotides are covalently linked by a condensation reaction

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16
Q

In the formation of a dinucleotide where does the linkage occur?

A

Between the phosphate group of one nucleotide and the sugar if another

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17
Q

What is the linkage in the formation of a nucleotide called?

A

A PHOSPHODIESTER bond

1 ester bond, 2 nucleotides joined

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18
Q

What is the backbone in DNA called?

A

A sugar phosphate backbone

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19
Q

What bases pair together in DNA?

A

Adenine and Thymine

Guanine and cytosine

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20
Q

What are DNAs bases joined by?

A

Hydrogen bonding

21
Q

What is DNAs structure?

A

A double stranded helix

22
Q

Is ribonuclease acid single stranded or double stranded?

A

Single

23
Q

What are the three types of RNA?

A
  • ribosomal RNA
  • transfer RNA
  • messenger RNA
24
Q

What is ribosomal RNA?

A

the structural component of ribosomes

25
Q

What does transfer RNA do?

A

It transports amino acids to ribosomes

26
Q

What does messenger RNA do?

A

It transfers genetic information from DNA to ribosomes

27
Q

What is ATP?

A

Adenosine triphosphate (energy)

28
Q

What biological processes require energy to occur?

A
  • muscle contraction
  • cell division
  • transmission of nerve impulses
  • memory formation
29
Q

What do cells require energy for? Give examples

A
  • synthesis -e.g. Of large molecules such as proteins
  • transport - e.g. Pumping molecules or ions across cell membranes by active transport
  • movement- e.g. Protein fibres in fibres of muscle cells that cause muscle contraction
30
Q

Where is ATP made and what is it?

A

It is made in the mitochondria and is a nucleic acid

31
Q

What base does ATP contain?

A

Adenine

32
Q

What is ATP made up of?

A
  • ribose (pentode sugar)
  • adenine
  • 3 phosphate groups
33
Q

What does AMP have? (adenosine monophosphate)

A

• 1 phosphate group

34
Q

What does ADP have (adenosine diphosphate)?

A

• two phosphates are joined

35
Q

What does ATP have? (Adenosine triphosphate)

A

• three phosphate groups

36
Q

What forms when ATP is broken down?

A

Breaks down to form ADP and a phosphate ion

37
Q

What reaction occurs to release energy from ATP?

A

• hydrolysis of the ATP releasing large amounts of energy which can be used for various energy requiring reactions

38
Q

Why is ATP used instead of glucose to release energy?

A
  • glucose takes too long to release energy and releases too much energy at once so it is wasted
  • so glucose is first turned to ATP and then broken down
39
Q

How is ATP formed?

A

By adding a phosphate group to a molecule of ADP

40
Q

What reaction occurs to form ATP from ADP?

A

A condensation reaction

41
Q

Where is energy supplied from in the reaction to form ATP?

A

Respiration

42
Q

What are the properties of ATP?

A
  • small
  • water soluble
  • immediate energy release
  • releases energy in small quantities
  • easily regenerated
43
Q

Why is it useful that ATP is small?

A

It can move in, out and within cells easily

44
Q

Why is it useful that ATP is water soluble?

A

Energy requiring processes occur in aqueous environments

45
Q

Why is it useful that properties of ATP allow easy energy release?

A

Bonds between phosphates allow for immediate energy release, they aren’t too large to be wasted, but large enough to be used for cellular reactions

46
Q

Why is it useful that energy is released in small quantities?

A

Energy is not wasted

47
Q

Why is it useful that ATP is easily regenerated?

A

It can be recharged with energy, ADP can do back to the mitochondria to make ATP

48
Q

Why does the reaction from ATP to ADP make energy instantly available?

A

It is a single reaction

49
Q

ATP + H2O =

A

ENERGY + ADP + Pi