2014 physiology midterm Flashcards

1
Q

What is the characteristic of action potential?

a. Greater stimulus produces greater magnitude of AP
b. Magnitude of AP decreases as you go away from the site of AP
c. Successive stimuli add up
d. All or none law

A

d. All or none law

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2
Q

Which ion increases inside the cells if acetylcholinesterase is inhibited?

a. Ca
b. Cl
c. Na
d. K

A

c. Na

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3
Q

What is the function of COPI?

a. Retrograded vesicle transport
b. Anterograde vesicle transport
c. Faster that COPII

A

a. Retrograded vesicle transport

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4
Q

What form as a result of union of the channel connexon?

a. Spectin
b. Integrin
c. Cadherin
d. Gap junction

A

d. Gap junction

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5
Q

In order for the neurotransmitters to be released in the synaptic gap, the level of intracellular Ca2+ must increase. Where does the Ca2+ come from?

a. Extracellular fluid
b. Endoplasmic reticulum
c. Mitochondria
d. Vesicles

A

a. Extracellular fluid

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6
Q

What force favors the movement from ISF to plasma?

a. Plasma pressure
b. Negative ISF pressure
c. Plasma colloid pressure
d. ISF colloid pressure

A

c. Plasma colloid pressure

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7
Q

By which mechanism/structure does antibody bound to FC receptor is transported through the cell from intracellular lumen to extracellular

a. Transcytosis
b. Exocytosis
c. Endocytosis

A

a. Transcytosis

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8
Q

What happens to the membrane potential if it becomes more negative than R.M.P?

a. Hyperpolarization
b. Depolarization
c. Repolarization

A

a. Hyperpolarization

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9
Q

Container A & B, A has “NaCl 1M + glucose 0.5M”. B has “KCl 0.5M”. What is the mV if there is permeability for Cl, Na, K, and glucose?

a. 98
b. 68
c. 0
d. -98
e. -68

A

c. 0

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10
Q

Which one of these stabilizes the steroid transcription factor receptor when it’s unbound?

a. Polymerase
b. Heat shock protein

A

b. Heat shock protein

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11
Q

(OUTSIDE – K = 5 & Na = 140) (INSIDE – K = 150 & Na = 14)
Calculate the mV if the cell is permeable only to K?

A

-90

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12
Q

(OUTSIDE – K = 5 & Na = 140) (INSIDE – K = 150 & Na = 14)
Calculate the equilibrium potential if all K and Na channels are open?

A

-3.26

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13
Q

(OUTSIDE – K = 5 & Na = 140) (INSIDE – K = 150 & Na = 14)
Calculate the equilibrium potential if all Na channels are open and half of K channels are open?

A

+12.46

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14
Q

Calculate EMF of Na, inside = 142 & outside = 14.2

A

-61mV

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15
Q

What is the osmotic pressure of 0.45% NaCl (Mwt = 58.5)?

A

2969

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16
Q

Where are neurotransmitters found in the presynaptic nerve in the absence of action potential?

a. In the cytoplasm, inside vesicles
b. In the ER, inside vesicles
c. In the synaptic space

A

a. In the cytoplasm, inside vesicles

17
Q

Homeostatic regulation for blood pressure is through communication between the brain and the heart, this control must be fast and sharply localized, which of the following is the best communication method?

a. Neural
b. Chemical
c. Paracrine
d. Endocrine

A

a. Neural

18
Q

A girl has body water of 60L with osmolarity of 300mosm/L, when she exercised she lost 1.5L and 200mosm/L. What is the osmolarity of her body after exercising?

A

302.56mosm/L

19
Q

Which one has the highest body water?

a. 20 years old male
b. 20 years old female
c. 70 years old male
d. Overweight 25 years old female

A

a. 20 years old male

20
Q

100ml of 2% NaCl + 400ml of 1% NaCl, what is the % of the solution?

A

a. 1.2%

21
Q

What is the consequence of the binding of insulin-like growth factor to its receptor?

a. Production of DAG
b. Generation of cAMP
c. Activation of TK

A

c. Activation of TK

22
Q

Acetylcholine binds to which of the following potassium-dependent channel?

a. Purinergic
b. Adrenergic
c. Muscarinic
d. Nictonic

A

c. Muscarinic

23
Q

Why is the concentration of Na+ in the plasma slightly higher than ISF?

A

Proteins have a negative charge and can’t pass through the capillary wall so they will attract the positive charge (donan effect)

24
Q

Locking the inhibition of adenylate cyclase because of a toxin results in what condition?

A

Whooping Cough

25
Q

Give an example of a type of transcription factor?

A

CREB

26
Q

Signals are secreted (nitric oxide) by one cell and diffused to adjacent cells or through local circulation is a type of local communication termed as…

A

Paracrine