[20] Drug Development and Pharmacology Flashcards
What topics are covered in the “Drug Development and Pharmacology” deck?
- Drug research and testing
- Preclinical trials
- Drug action and interaction
- Pharmacokinetics
- Pharmacodynamics
Define ‘Drug Development’
A process to introduce a new pharmaceutical drug to the market
What does ‘Pharmacology’ study?
The study of drug action on biological systems
What is the purpose of ‘Preclinical Trials’?
They test a drug’s safety and efficacy before it is tested on humans
Explain ‘Drug Action and Interaction’
The processes by which drugs produce changes in the function of body cells
Define ‘Pharmacokinetics’
The study of what the body does to a drug
Define ‘Pharmacodynamics’
The study of what a drug does to the body
Why is ‘Drug Development and Pharmacology’ crucial?
It helps in the development and testing of potential therapeutics
What are the key phases in ‘Drug Development’?
- Drug discovery
- Preclinical research
- Clinical trials
- FDA review
- FDA post-market safety monitoring
What is involved in ‘Preclinical Trials’?
- In vitro testing
- Animal testing
What are the main types of ‘Drug Interactions’?
- Drug-Drug interaction
- Drug-Food interaction
- Drug-Alcohol interaction
What are the four stages of ‘Pharmacokinetics’?
- Absorption
- Distribution
- Metabolism
- Excretion
What are the main components of ‘Pharmacodynamics’?
- Receptor binding
- Post-receptor effects
- Chemical interactions
Define ‘In Vitro Testing’
Testing performed in a controlled environment, like a test tube
Define ‘Animal Testing’
Testing performed on non-human animals
What is ‘Drug-Drug Interaction’?
When a drug affects the activity of another drug when both are administered together
What is ‘Drug-Food Interaction’?
When food affects the activity of a drug
What is ‘Drug-Alcohol Interaction’?
When alcohol affects the activity of a drug
Define ‘Absorption’ in pharmacokinetics
The process of a drug entering the systemic circulation
Define ‘Distribution’ in pharmacokinetics
The dissemination of a drug to the body tissues
Define ‘Metabolism’ in pharmacokinetics
The biotransformation of a drug into an inactive compound
Define ‘Excretion’ in pharmacokinetics
The elimination of the inactive compounds from the body
