[08] Bioinformatics Flashcards

1
Q

What topics are included in the “Bioinformatics” deck?

A
  • Basics of bioinformatics
  • Sequence alignment
  • Database use
  • Genomic and proteomic data analysis
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2
Q

Define ‘Bioinformatics’

A

An interdisciplinary field that develops methods and software tools for understanding biological data

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3
Q

What is ‘Sequence Alignment’ in bioinformatics?

A

The process of arranging sequences of DNA, RNA, or protein to identify regions of similarity

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4
Q

What does ‘Database Use’ in bioinformatics refer to?

A

The utilization of biological databases for storing, retrieving, and analyzing biological sequences

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5
Q

Define ‘Genomic Data Analysis’

A

The process of examining and interpreting data from DNA sequences

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6
Q

What is ‘Proteomic Data Analysis’?

A

The process of examining and interpreting data from protein sequences

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7
Q

Why is ‘Bioinformatics’ crucial?

A

For understanding and interpreting complex biological data sets

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8
Q

What are the key components in ‘Sequence Alignment’?

A
  • Query sequence
  • Reference sequence
  • Alignment algorithm
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9
Q

How is ‘Database Use’ important in bioinformatics?

A

It allows researchers to access, compare, and analyze vast amounts of biological data

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10
Q

What is involved in ‘Genomic Data Analysis’?

A
  • Genome sequencing
  • Genome annotation
  • Genomic variation analysis
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11
Q

What processes are part of ‘Proteomic Data Analysis’?

A
  • Protein identification
  • Protein structure analysis
  • Protein-protein interaction analysis
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12
Q

Name some commonly used databases in bioinformatics

A
  • GenBank
  • PDB (Protein Data Bank)
  • UniProt
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13
Q

What is DNA?

A

Deoxyribonucleic acid, the molecule that carries genetic instructions in all living organisms

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14
Q

What is RNA?

A

Ribonucleic acid, a molecule involved in various biological roles including coding, decoding, regulation and expression of genes

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15
Q

Define ‘Protein’

A

A large molecule composed of one or more chains of amino acids in a specific order

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16
Q

What is a ‘genome’?

A

The complete set of genes or genetic material present in a cell or organism

17
Q

What is ‘genomic variation’?

A

Differences in the genetic makeup among individuals in a population

18
Q

What does PDB stand for?

A

Protein Data Bank

19
Q

What is GenBank?

A

A genetic sequence database, an annotated collection of all publicly available DNA sequences

20
Q

What is UniProt?

A

The Universal Protein resource, a comprehensive resource for protein sequence and annotation data