2. Immune response- cells

Question 1

Role of WBCs - neutrophil

Answer 1

Phagocytosis

Question 2

Role of B cells

Answer 2

Part of antibody Mediated Immune Response
- Produce antibodies
- Antibodies bind and destroy the specific antigen

Question 3

Name the 5 T-cells involved in the cell mediated Immune response.

Answer 3

• Helper T-cells CD4+
• Cytotoxic CD8+
• Natural Killer t-cells
• Regulatory T-cells (CD8+)
• Memory T-cells

Question 4

What do helper T-cells do?

Answer 4

Stimulate B cells to make antibodies

Question 5

What do cytotoxic T-cells do?

Answer 5

Need activation to bind to the antigen and destroy it

Question 6

What do Natural killer T-cells (innate) do?

Answer 6

Don’t need activation to attack harmful cells

Question 7

What do Regulatory T-cells (innate) do?

Answer 7

Turn off immune response once infection is destroyed

Question 8

What do memory T-cells do?

Answer 8

Long lived immunity

Question 9

Role of WBCs - Macrophage

Answer 9

Phagocytosis
Antigen-presenting cell

Question 10

Role of WBCs - Dendrite

Answer 10

Antigen- presenting cell

Question 11

Role of WBCs - Basophil

Answer 11

• Part of inflammatory response
• Release Heparin (prevents blood from clotting too quickly)
• Release Histamine (enlarges blood vessels to improve blood flow and heal)

Question 12

Role of WBCs - Mast cells

Answer 12

Part of Inflammatory response
Detect ALLERGENS and then ..
Release Histamine (enlarges blood vessels to improve blood flow and heal)
Hypersensitivity

Question 13

Role of WBCs - Lymphocytes

Answer 13

Turn into B + T cells

Question 14

Role of WBCs - Eosinophils

Answer 14

Release toxic chemicals

Question 15

Role of T cells

Answer 15

cell-mediated (does not involve antibodies) immune response

Question 16

Role of WBCs - monocytes

Answer 16

immune cell made in the bone marrow. Turns into a macrophage or dendritic cells

Question 17

Role of Hematopoietic stem cells

Answer 17

An immature cell that can develop into any blood cell (WBCs RBCs + platelets)

Question 18

What are CD8+?

Answer 18

Cytotoxic T cells, Regulatory T-cells

Question 19

What are CD4+?

Answer 19

Helper T-cells

Question 20

What are the Innate responses?

Answer 20

present at birth * Phagocytic cells (non-adaptive WBCs) * Not adaptive “

Question 21

What is the role of the lymphatic system?

Answer 21

The lymphatic system is our body’s ‘sewerage system’.
- Maintains fluid levels in our body tissues by removing all fluids that leak out of our blood vessels
- general and specific immune responses
- absorbing digestive tract fats
- removing cellular waste

Question 22

Thinking about antibody structure and function. What is Neutralisation?

Answer 22

The ability of antibodies to block the site(s) of bacteria or viruses that they use to enter their target cell.
(Neutralising it at the active site, preventing it from binding)

Question 23

Thinking about antibody structure and function. What is Opsonisation?

Answer 23

antibody opsonization is a process by which a pathogen is marked for phagocytosis. (Without an opsonin, such as an antibody, the negatively-charged cell walls of the pathogen and phagocyte repel each other)

Question 24

Thinking about antibody structure and function. What is Complement Fixation?

Question 25

Complement Fixation, Opsonisation and neutralisation are all examples of what ?

Answer 25

Antibody structure/ function