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Goljan > 17. Hematology > Flashcards

17. Hematology Flashcards

1
Q

What’s the most common factor deficiency?

A

Factor VIII

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2
Q

What do you use to follow warfarin?

A

PT

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3
Q

What is PTT in warfarin?

A

Prolonged - because common pathway is also affected (PT just does a better job of following warfarin)

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4
Q

What is PT in heparin?

A

Prolonged - because common pathway is also affected (PTT just does a better job of following heparin)

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5
Q

What’s the best test for DIC?

A

D-dimers (fibrin split products - fibrin that is crosslinked)

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6
Q

Small red dots everywhere - telangiectasias?

A

Hereditary telangiectasias - iron deficiency anemia from GI bleeds

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7
Q

HSR of ITP?

A

II

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8
Q

What happens in ITP?

A

IgG against platelets

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9
Q

TTP/HUS vs. DIC?

A

TTP/HUS has normal coagulation factors; not using those up

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10
Q

What do we see on blood smear for TTP?

A

schistocytes

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11
Q

Hem A vs. vWD?

A

vWD has factor 8 deficiency in addition to platelet problems - menorrhagia in addition to petechiae, etc.

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12
Q

What is drug of choice for vWD?

A

Desmopressin (DDAVP)

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13
Q

Why does amniotic fluid in the circulation cause problems?

A

Thromboplastin –> DIC

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14
Q

What is the most common hereditary thrombosis?

A

Factor V Leiden

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15
Q

Hx of thrombosis, patient started on heparin, PTT is normal - diagnosis?

A

Antithrombin III deficiency

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16
Q

What is the most common way antithrombin III deficiency is acquired?

A

OCP’s

17
Q

anti-A and anti-B blood group antibodies are what kind of immunoglobulin?

A

IgM

18
Q

What groups of patients have low/no blood group immunoglobulins?

A

Babies and elderly

19
Q

What blood group is associated with gastric cancer?

A

A

20
Q

What blood group is associated with ulcers?

A

O

21
Q

Why are blacks less likely to get plasmodium vivax?

A

Black populations lack duffy antigen on erythrocytes which vivax needs to infect

Goljan (21 decks)

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