15c alteration to thrombocyte Flashcards
TYPES OF APHERESIS
REMOVAL OF PLASMA AND COMPONENTS
platelet pheresis leukapheresis plasmapheresis stem cell harvest erythrocytapheresis
BLOOD DONATION
To protect both the donor and the recipients,
all
prospective blood donors must complete a
questionnaire and be examined and interviewed
before donating their blood.
blood donation criteria
Different criteria exist for the donation of red cells
and plasma.
Body weight should exceed 50 kg for a standard 470
mL donation.
Donors must be between the ages of 16 and 70 years
BLOOD TRANSFUSION
What do you check besides the 5 rights when administering blood?
Check patient has a patent cannula before priming blood in infusion set.
[Change IV tubing every 12 h, or with new IV fluids, with a platelet
transfusion or on completion of transfusion, whichever comes first].
Check patient has given consent
Make sure that PRBC transfusion is initiated within 30 min after removal of
the PRBCs from the blood bank refrigerator.
Check details of prescription/order against the blood bag AND the product
compatibility report, (Blood group, Rh factor)
Check the blood for gas bubbles and any unusual colour or cloudiness. (Gas
bubbles may indicate bacterial growth. Abnormal colour or cloudiness may
be a sign of haemolysis.)
Check use by date
Check temperature (should not be cold/incorrectly stored)
Pharmacological agents to stimulate production of one or more
types of blood cells by the marrow are commonly used.
(Growth
factors, erythropoietin, thrombopoeitin, iron replacement
therapy)
who outline appropriate assessment and
interventions in order to address anomalies (blood)
The Australian National Blood Authority Patient Blood
Management Guidelines
Researchers continue to seek a blood substitute
that is practical
and safe. Manufacturing artificial blood is problematic, given the
myriad functions of blood components.
Desmopressin
is a synthetic hormone that may help control bleeding. It
can be injected intravenously, administered under the skin
(subcutaneously), or given as a nasal spray. Desmopressin does not work
for every platelet disorder or individual.
Desmopressin works on
is used to help stop bleeding in patients with
von Willebrand’s disease or mild haemophilia A.
DDAVP causes the release o
f von Willebrand’s antigen from the platelets
and the cells that line the blood vessels where it is stored. Von
Willebrand’s antigen is the protein that carries factor VIII. This increase
in von Willebrand’s antigen and factor VIII helps to stop bleeding