immune system 5 Flashcards
HYPERSENSITIVITY OF THE IMMUNE
SYSTEM
Autoimmunity
• Isoimmunity—
• Acquired immune deficiency
Autoimmunity
—inappropriate, excessive response to self-antigens
üCauses autoimmune diseases
üSystemic lupus erythematosus (SLE)—chronic inflammatory disease caused by numerous antibodies attacking a variety of tissues
Isoimmunity
excessive reaction to antigens from another human
üCan occur between mother and foetus during pregnancy (Anti D)
üCan occur in tissue transplants (causing rejection syndrome)
• Acquired immune deficiency
üDevelops after birth
üAcquired immunodeficiency syndrome (AIDS)—caused by HIV infection of T cells
What is angioedema?
caused by a rapid increase in permeability of subcutaneous capillaries and post-capillary venules with localized plasma extravasation.
result of an allergic reaction. This is where the body mistakes a harmless substance, such as a certain food, for something dangerous. It releases chemicals into the body to attack the substance, which cause the skin to swell.
What are the signs and symptoms of angioedema?
Welts that form in minutes to hours.
(3 days to hours) Rash
Swelling and redness, especially around the eyes, cheeks or lips.
Pain or warmth in the affected areas.
Dizziness stomach pain
What are some of the causes of angioedema?
allergic reaction to: certain types of food
some types of medicine – including some antibiotics, aspirin and non-steroidal anti-inflammatory drugs (NSAIDs),
insect bites and stings – particularly wasp and bee stings.
What is the primary goal and medical management for angioedema?
Histamine-mediated angioedema should be treated with epinephrine intramuscularly,
antihistaminergic medications
steroids
What is the difference between angioedema and anaphylaxis?
angioedema is not that life threatening and can resolve from hours to days.
Angioedema can be life-threatening if swelling causes your throat or tongue to block your airway.
anaphylaxis is life threatening, signs of anaphylaxis is angioedema
what is anaphylaxis
a severe, potentially life-threatening allergic reaction.
that needs to be treated right away. If you have an anaphylactic reaction, you need an epinephrine (adrenaline) shot as soon as possible, deadly
CAUSES adenoma
Foods - peanut, tree nuts, cow milk, eggs, soy,
shellfish, fish, wheat, kiwi fruit
• Bites/stings - Bees, wasps, ants, jellyfish
• Medications- ABx
• Other - exercise, idiopathic