14.1 Hormonal Coordination Flashcards
Endocrine gland
Group of cells specialised to secrete hormones into the bloodstream
Pituitary gland functions
- produces growth hormone (growth of bones and muscles)
- ADH (reabsorption of water)
- gonadotropins (development of ovaries and testes)
Pineal gland function
Produces melatonin - affects reproductive development and daily cycles
Thymus function
Produces thymosin - promotes production and maturation of WBCs
Pancreas function
- insulin (glucose to glycogen conversion) when glucose levels increase
- glucagon (glycogen to glucose) when glucose levels fall
Ovary functions
- produces oestrogen - ovulation and secondary sexual characteristics
- progesterone - prepares uterus lining to receive embryo
Thyroid gland function
Produces thyroxine which controls rate of metabolism and rate that glucose is used up in respiration - promotes growth
Adrenal gland function
Produces adrenaline which increases heart and breathing rate and raises blood glucose level
Testes function
Produces testosterone - controls sperm production and secondary sexual characteristics
What happens when hormones are secreted?
Transported in blood plasma around the body
Hormones diffuse out of blood and bind to specific receptors for that hormone
Receptors are found in membranes/in cytoplasm of target organs - target cells
Two types of hormone
Steroid hormones
Non steroid hormones
Steroid hormones
Lipid soluble
Can pass through cell membrane
How do steroid hormones work?
Pass through cell membrane
Bind to steroid hormone receptor to form hormone receptor complex
Receptors can be in cytoplasm or nucleus
Hormone receptor complex acts as a transcription factor - can facilitate or inhibit transcription of a particular gene
Complex attaches to DNA, which provides instructions for synthesis of a polypeptide
Polypeptide synthesised by ribosomes and mRNA
Non steroid hormones
Hydrophilic
Cannot pass through cell membrane
How do steroid hormones work?
Bind to specific receptors on cell surface membrane of target cell
Triggers cascade reaction by second messengers