00 Male Issues Flashcards
What is the normal range for Prostate Specific Antigen (PSA)?
0-4 ng/mL
What are some medications that may worsen BPH?
Anticholinergics (TCAs, antipsychotics, etc), Antihistamines, Decongestants, Diuretics, Caffeine
What is the generic name of Hytrin?
Terazosin - BPH (Non-selective Alpha-1 blocker)
What is the generic name of Cardura?
Doxazosin - BPH (Non-selective Alpha-1 blocker)
What is the generic name of Uroxatral?
Alfuzosin - BPH (Non-selective Alpha-1 blocker)
What is the generic name of Flomax, Jalyn?
Tamsulosin - BPH (Selective Alpha-1a blocker)
What is the generic name of Rapaflo?
Silodosin - BPH (Selective Alpha-1a blocker)
What is important to know about Alpha-1 blockers in BPH?
1st dose phenomenon (orthostatic hypotension), dose at night. Does NOT affect PSA levels nor shrink the prostate. Can cause Priapism
What is important to know about 5-alpha reductase inhibitors in BPH?
Associated with prostate SHRINKAGE and symptom improvement. Delayed onset of response vs alpha blockers
What is the generic name of Proscar?
Finasteride - BPH (5-alpha reductase inhibitor)
What is the generic name of Avodart, Jalyn?
Dutasteride - BPH (5-alpha reductase inhibitor)
What pregnancy category are the 5-alpha reductase inhibitors used for BPH?
Category X
What are the main ADRs for 5-alpha reductase inhibitors for BPH?
Sexual dysfunction, Breast swelling and tenderness
What is the generic name of Viagra?
Sildenafil (PDE-5 inhibitor)
What is the generic name of Cialis?
Tadalafil (PDE-5 inhibitor)