00 Antibiotics Flashcards
What is the generic name of Amoxil?
Amoxicillin (Aminopenicillin)
What is the generic name of Augmentin?
Amoxicillin + Clavulanate (Aminopenicillin)
What is the generic name of Amoclan?
Amoxicillin + Clavulanate (Aminopenicilln)
What is the generic name of Unasyn?
Ampicillin + Sulbactam (Aminopenicillin)
What is the generic name of Pen VK?
Penicillin (Natural penicillin)
What is the generic name of Bicillin L-A?
Penicillin G Benzathine (Natural penicillin)
What is the generic name of Zosyn?
Piperacillin + Tazobactam (Ureidopenicillin)
What class of medication is Nafcillin?
Penicillin
What class of medication is Gentamicin?
Aminoglycoside
What class of medication is Tobramycin?
Aminoglycoside
What class of medication is Amikacin?
Aminoglycoside
What is the generic name of Kefzol?
Cefazolin (1st gen ceph)
What is the generic name of Keflex?
Cephalexin (1st gen ceph)
What is the generic name of Ceftin?
Cefuroxime (2nd gen ceph)
What is the generic name of Zinacef?
Cefuroxime (2nd gen ceph)
What class of medication is Cefotetan?
2nd gen ceph
What class of medication is Cefoxitin?
2nd gen ceph
What is the generic name of Fortaz?
Ceftazidime (3rd gen ceph)
What is the generic name of Tazicef?
Ceftazidime (3rd gen ceph)
What is the generic name of Rocephin?
Ceftriaxone (3rd gen ceph0
What class of medication if Cefdinir?
3rd gen ceph
What is the generic name of Maxipime?
Cefepime (4th gen ceph)
What is the generic name of Teflaro?
Ceftaroline (5th gen ceph)
What is the generic name of Primaxin?
Imipenem/Cilastatin (Carbapenem)
What is the generic name of Merrem?
Meropenem (Carbapenem)
What is the generic name of Invanz?
Ertapenem (Carbapenem)
What is the generic name of Doribax?
Doripenem (Carbapenem)
What class of medication is Ofloxacin?
FQ
What is the generic name of Cipro?
Ciprofloxacin (FQ)
What is the generic name of Levaquin?
Levofloxacin (FQ)
What is the generic name of Avelox?
Moxifloxacin (FQ)
What is the generic name of Zithromax or Z-pak?
Azithromycin (Macrolide)
What is the generic name of Biaxin?
Clarithromycin (Macrolide)
What is the generic name of Ery-tab, EryPed?
Erythromycin (Macrolide)
What class of medication is Doxycycline?
Tetracycline
What class of medication is Minocycline?
Tetracycline
What is the generic name of Septra?
SMX/TMP (Sulfonamide)
What is the generic name of Sulfatrim?
SMX/TMP (Sulfonamide)0
What is the generic name of Vancocin?
Vancomycin
What is the generic name of Zyvox?
Linezolid
What is the generic name of Synercid?
Quinupristin/Dalfopristin
What is the generic name of Cubicin?
Daptomycin
What is the generic name of Azactam?
Aztreonam
What is the generic name of Colistin?
Colistamethate
What is the generic name of Tygacil?
Tigecycline
What is the generic name of Cleocin?
Clindamycin
What is the generic name of Flagyl?
Metronidazole
What is the generic name of Xifaxan?
Rifaximin
What is the generic name of Macrobid?
Nitrofurantoin
What is the generic name of Furadantin?
Nitrofurantoin
What is the generic name of Macrodantin?
Nitrofurantoin
What is the generic name of Dificid?
Fidaxomicin
What is the first agent used for skin and skin structure infections caused by CA-MRSA?
SMX-TMP (Bactrim DS) 1-2 DS tabs Q12h
What is the first agent used to treat Nosocomial-Associated MRSA?
Vancomycin
What is the first agent used to treat VRE faecalis?
Pen G or Ampicillin
What is the first agent used to treat VRE faecium?
Daptomycin
What is the first agent used to treat Extended Spectrum Beta-Lactamase producuding Enteric Gram-negative Rods (PEK)
Carbapenems
What is the first agent used to treat Acinetobacter baumannii?
Carbapenems
What are the more hepatotoxic antibiotics?
Rifampin. Macrolides (not as bad)
What are the most nephrotoxic antibiotics?
Aminoglycosides. Colistin
Which antibiotics can cause QT prolongation?
Macrolides. Quinolones. SMX/TMP
In general, what are the drugs of choice for most procedures?
1st or 2nd gen cephs (cefazolin/cefuroxime). In PCN-allergic patients, a suitable alternative is vancomycin (given 2 hours prior to surgical incision)
What is usually given for surgeries that involve parts of the bowel or put patients at risk of an anaerobic infection?
Commonly use antibiotics with broader coverage such as Cefotetan, Ertapenem, or Ceftriaxone with Metronidazole
What are the side effects associated with Aminoglycosides?
Nephrotoxicity (acute tubular necrosis - ATN), Hearing loss (early toxicity associated with high pitched sounds)
What are the BBWs associated with Aminoglycosides?
Neurotoxicity (hearing loss), Nephrotoxicity
What class side effect of Carbapenems should you keep an eye out for?
Seizures
What is the BBW associated with Fluoroquinolones?
Tendon inflammation and/or rupture
What are the warnings associated with Fluoroquinolones?
QT prolongation. Peripheral neuropathy. CNS effects (seizures may occur). Hypoglycemia. Photosensitivity
What are the common side effects seen with Fluoroquinolones?
GI upset/diarrhea
What are the warnings associated with Macrolides?
QT prolongation. Hepatotoxicity
Whats a common side effect seen with Tetracyclines?
Photosensitivity
Whats important to remember about Doxycycline IV?
IV to PO ratio is 1:1. IV should be protected from light
What are the side effects commonly seen with sulfonamide drugs (Bactrim)?
GI upset, skin reactions, crystalluria, photosensitivity, hyperkalemia, hypoglycemia
Whats important to know about the IV and PO ratio of Bactrim?
1:1 ratio
What side effects are commonly seen with Vancomycin?
Infusion reaction/red man syndrome. Nephrotoxicity
When is Zyvox (Linezolid) contraindicated?
Concurrent use or within 2 weeks of MAOIs
What side effects are commonly seen with Synercid (Quinupristin/Dalfopristin)?
Arthralgias/myalgias, infusion reactions, including edema and pain at infusion site, phlebitis, hyperbilirubinemia
What are the BBWs with Vibativ (Telavancin)?
Nephrotoxicity. Warning: Prolongs QT interval, red man syndrome
What is a BBW with Tygacil (Tigecycline)?
Increased risk of death, should only be used in situations when alternative treatments are not suitable
What is a BBW with Cleocin (Clindamycin)?
Can cause severe and possibly fatal colitis
What is a contraindication for Flagyl (Metronidazole) use?
Use of alcohol during therapy or within 3 days of therapy discontinuation
What are some common antibiotics that require refrigeration?
Amox/Clav (Augmentin), Cefprozil, Cefuroxime (Ceftin), Cephalexin (Keflex), Pen VK