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Board Study Topics > 00 Antiemetics > Flashcards

00 Antiemetics Flashcards

1
Q

What is the generic name for Anzemet?

A

Dolasetron (5-HT3 Receptor Antagonist)

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2
Q

What is the generic name for Sancuso?

A

Granisetron (used to be called Kytril) (5-HT3 Receptor Antagonist)

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3
Q

What is the generic name for Zofran?

A

Ondansetron (5-HT3 Receptor Antagonist)

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4
Q

What is the generic name for Zuplenz?

A

Ondansetron Oral Soluble Film (5-HT3 Receptor Antagonist)

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5
Q

What is a common ADR with the 5-HT3 Receptor Antagonists?

A

Headaches, Diarrhea

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6
Q

What is the generic name for Aloxi?

A

Palonosetron (5-HT3 Receptor Antagonist)

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7
Q

What is the generic name for Emend?

A

Aprepitant (Substance P/Neurokinin-1 (NK-1) Receptor Antagonist)

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8
Q

What is the generic name for Reglan?

A

Metoclopramide (DA-Blocking Agent)

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9
Q

What is the generic name for Compazine?

A

Prochlorperazine (Phenothiazine (DA-blocking agent))

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10
Q

What is the generic name for Phenergan?

A

Promethazine (Phenothiazine (DA-blocking agent))

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11
Q

What is the generic name for Tigan?

A

Trimethobenzamide (Anticholinergic/Antimuscarinic)

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12
Q

What is the generic name for Antivert?

A

Rx Meclizine (Anticholinergic/Antimuscarinic)

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13
Q

What is the generic name for Unisom?

A

Doxylamine (Anticholinergic/Antimuscarinic)

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14
Q

What is the generic name for Emetrol?

A

Phosphorated carbohydrates (careful with diabetics, will raise BG)

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15
Q

What is the generic name for Marinol?

A

Dronabinol (Cannabinoid Receptor Agonist) C-III

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16
Q

How is Aprepitant used?

A

NOT indicated for monotherapy: aprepitant should only be used in combination with 5-HT3 receptor antagonist and a corticosteroid (studies used it with dexamethasone + ondansetron)

17
Q

What toxicity needs to be monitored for Reglan (Metoclopramide)?

A

Tardive Dyskinesia (TD) since it is a DA-blocking agent

18
Q

What is the generic name for Cesamet?

A

Nabilone (Cannabinoid Receptor Agonist) C-II

19
Q

Which 5-HT3 antagonist comes in a patch form?

A

Granisetron

20
Q

Which agent should not be co-administered with apomorphine because of severe hypotensive effects that may result if used together?

A

Ondansetron

21
Q

Which class of antiemetics should a patient avoid if he is taking donepezil for Alzheimer’s Disease?

A

Anticholinergics

22
Q

Which antiemetic should a patient avoid if she is not well-controlled on a Parkinson’s Disease medication that is making her nauseous?

A

Metoclopramide

23
Q

Which agents would you recommend to be used with doxylamine for your pregnant patient who is experiencing hyperemesis gravidum (extreme N/V during pregnancy)?

A

Pyridoxine

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