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Board Study Topics > 00 Alzheimer's Disease > Flashcards

00 Alzheimer's Disease Flashcards

1
Q

What are the two medication classes used for Alzheimer’s Disease?

A

Acetylcholinesterase Inhibitors (prolong ACh activity). NMDA antagonists

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2
Q

What medication class should people with AD avoid?

A

Anticholinergics (worsen memory impairment)

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3
Q

What is the generic name of Aricept?

A

Donepezil (Acetylcholinesterase Inhibitor)

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4
Q

What are the ADRs seen with Aricept (Donepezil)?

A

N/V/D, Bradycardia

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5
Q

Which Acetylcholinesterase Inhibitor comes with an ODT option?

A

Aricept (Donepezil)

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6
Q

What is the generic name of Razadyne?

A

Galantamine (Acetylcholinesterase Inhibitor)

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7
Q

What is the generic name of Exelon?

A

Rivastigmine (Acetylcholinesterase Inhibitor)

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8
Q

What is the generic name of Namenda?

A

Memantine (NMDA Receptor Antagonist)

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9
Q

What is a class effect of Acetylcholinesterase Inhibitor’s?

A

N/V/D, Bradycardia

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10
Q

Which Acetylcholinesterase Inhibitor causes the most N/V?

A

Exelon (Rivastigmine), has a BOLD warning for N/V –> watch for anorexia, weight loss

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11
Q

What are the ADRs seen with Namenda (Memantine)?

A

Dizziness, HA

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12
Q

Why do we generally avoid using Cognex (Tacrine - Acetylcholinesterase Inhibitor)?

A

Increases LFTs, causes liver damage

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13
Q

Which Acetylcholinesterase Inhibitor has little P450 involvement?

A

Exelon (Rivastigmine)

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14
Q

What does NMDA stand for?

A

N-Methyl-D-Aspartate

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15
Q

How is Namenda (Memantine) dosed?

A

5mg QD x 1 week, 5mg BID x 1 week, 10mg Qam, 5mg Qnoon. Increase to 10mg BID by week 4

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16
Q

Which Acetylcholinesterase Inhibitor should be taken on an empty stomach?

A

Cognex (Tacrine)

17
Q

Which Acetylcholinesterase Inhibitor should be taken with meals?

A

Razadyne (Galantamine). Exelon (Rivastigmine)

18
Q

Which Acetylcholinesterase Inhibitor’s are available as oral solutions?

A

Razadyne (Galantamine). Exelon (Rivastigmine)

Board Study Topics (38 decks)

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