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MSK II > Zoonotic skin infections > Flashcards

Zoonotic skin infections Flashcards

1
Q

Gram positive, large, rectangular rods arranged in chains that are non-motile and capsulated

A

Bacillus anthracis

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2
Q

Polypeptide capsule composed of D-glutamate coded by plasmid that inhibits phagocytosis

A

Bacillus anthracis

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3
Q

Anthrax toxin

A

Edema and lethal
Controlled by plasmid, pXO1

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4
Q

Starts as painless papule 1-7 days after exposure. Marked erythema and edema are seen with progression to ulceration with surrounding vesicles. Rupture leads to eschar formation

A

Cutaneous anthrax

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5
Q

Bacillus anthracis on blood agar

A

Non-hemolytic colonies with frosted glass and/or medusa head appearance

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6
Q

Gram negative bacilli in polysaccharide protein capsule that produces endotoxin and exotoxin. Giemsa stain shows bipolar staining and safety pin appearance.

A

Yersinia pestis

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7
Q

Type III secretion system of Yersinia pestis

A

Inhibit phagocytosis
Suppression of cytokine production

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8
Q

Complications of Yersinia pestis

A

Pneumonia
DIC
Septicemia

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9
Q

Treatment for plague

A

Streptomycin
Chloramphenicol
Tetracycline

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10
Q

Leptospiral serogroups

A

Canicola
Icterohemoorrhagiae
Hebdomadis

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11
Q

Risk factors for leptospirosis

A

Outdoor activities and watersports

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12
Q

Weil disease

A

Extensive vasculitis, myocarditis, renal and hepatic failure, and death

In leptospirosis

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13
Q

Demonstrated on dark ground microscopy or silver staining

A

Leptospirosis

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14
Q

Treatment for leptospirosis

A

Penicillin
Doxycycline

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15
Q

Gram negative coccobacilli transmitted though cat scratch/bit or cat flea

A

Bartonella henselae

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16
Q

Post-infection complication of Cat’s scratch disease in immunocompromised

A

Subacute bacterial endocarditis

17
Q

Treatment for cat’s scratch disease

A

Erythromycin
Azithromycin
Doxycycline

18
Q

Very small, intracellular, faintly stained, gram negative coccobacilli that is encapsulate and strictly aerobic

A

Francisella tularensis

19
Q

Skin lesion starts as painful papule at site of inoculation which then ulcerates with a necrotic center and raised border

A

Tularemia

20
Q

Treatment of tularemia

A

Gentamicin - preferred
Doxycycline or cipro in mild infection

21
Q

Histology of brucella species

A

Gram negative coccobacilli

22
Q

Treatment of brucellosis

A

Tetracyclines
Aminoglycosides

23
Q

Gram negative, short, encapsulated rod with bipolar staining that is part of the normal flora of cats and dogs

A

Pasteurella multocida

24
Q

Virulence factor of Pasteurella multocida

A

Endotoxin

25
Q

Symptoms of pasteurellosis

A

Wound infection
Cellulitis with lymphadenitis
Osteomyelitis

26
Q

Complication of pasteruellosis

A

Chronic respiratory disease

27
Q

Early symptoms of chills, fever, and myalgia followed 1-2 days later by dry cough, HA, N/V, and SOB

A

Hantavirus

MSK II (16 decks)

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