Zoonotic skin infections

Question 1

Gram positive, large, rectangular rods arranged in chains that are non-motile and capsulated

Answer 1

Bacillus anthracis

Question 2

Polypeptide capsule composed of D-glutamate coded by plasmid that inhibits phagocytosis

Answer 2

Bacillus anthracis

Question 3

Anthrax toxin

Answer 3

Edema and lethal
Controlled by plasmid, pXO1

Question 4

Starts as painless papule 1-7 days after exposure. Marked erythema and edema are seen with progression to ulceration with surrounding vesicles. Rupture leads to eschar formation

Answer 4

Cutaneous anthrax

Question 5

Bacillus anthracis on blood agar

Answer 5

Non-hemolytic colonies with frosted glass and/or medusa head appearance

Question 6

Gram negative bacilli in polysaccharide protein capsule that produces endotoxin and exotoxin. Giemsa stain shows bipolar staining and safety pin appearance.

Answer 6

Yersinia pestis

Question 7

Type III secretion system of Yersinia pestis

Answer 7

Inhibit phagocytosis
Suppression of cytokine production

Question 8

Complications of Yersinia pestis

Answer 8

Pneumonia
DIC
Septicemia

Question 9

Treatment for plague

Answer 9

Streptomycin
Chloramphenicol
Tetracycline

Question 10

Leptospiral serogroups

Answer 10

Canicola
Icterohemoorrhagiae
Hebdomadis

Question 11

Risk factors for leptospirosis

Answer 11

Outdoor activities and watersports

Question 12

Weil disease

Answer 12

Extensive vasculitis, myocarditis, renal and hepatic failure, and death

In leptospirosis

Question 13

Demonstrated on dark ground microscopy or silver staining

Answer 13

Leptospirosis

Question 14

Treatment for leptospirosis

Answer 14

Penicillin
Doxycycline

Question 15

Gram negative coccobacilli transmitted though cat scratch/bit or cat flea

Answer 15

Bartonella henselae

Question 16

Post-infection complication of Cat’s scratch disease in immunocompromised

Answer 16

Subacute bacterial endocarditis

Question 17

Treatment for cat’s scratch disease

Answer 17

Erythromycin
Azithromycin
Doxycycline

Question 18

Very small, intracellular, faintly stained, gram negative coccobacilli that is encapsulate and strictly aerobic

Answer 18

Francisella tularensis

Question 19

Skin lesion starts as painful papule at site of inoculation which then ulcerates with a necrotic center and raised border

Answer 19

Tularemia

Question 20

Treatment of tularemia

Answer 20

Gentamicin - preferred
Doxycycline or cipro in mild infection

Question 21

Histology of brucella species

Answer 21

Gram negative coccobacilli

Question 22

Treatment of brucellosis

Answer 22

Tetracyclines
Aminoglycosides

Question 23

Gram negative, short, encapsulated rod with bipolar staining that is part of the normal flora of cats and dogs

Answer 23

Pasteurella multocida

Question 24

Virulence factor of Pasteurella multocida

Answer 24

Endotoxin

Question 25

Symptoms of pasteurellosis

Answer 25

Wound infection Cellulitis with lymphadenitis Osteomyelitis

Question 26

Complication of pasteruellosis

Answer 26

Chronic respiratory disease

Question 27

Early symptoms of chills, fever, and myalgia followed 1-2 days later by dry cough, HA, N/V, and SOB

Answer 27

Hantavirus