Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MSK II > Mucocutaneous lesions > Flashcards

Mucocutaneous lesions Flashcards

1
Q

Viruses that cause maculopapular rashes

A

Measles/rubeola
Rubella
Roseola/HHV-6
Fifth disease/parvovirus B19

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Viruses that cause vesicular rashes

A

Chickenpox/VZV
Hand-foot-mouth/Coxsackie
HSV-1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Virus that attaches to CD46, PVRL4, and CD150 receptors of many cells

A

Measles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Maculopapular rash that starts on face and spreads to extremities

A

Measles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Presentation of measles

A

CCCP –> cough, coryza, conjunctivitis, and photophobia

High fever
Exanthema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Exanthema

A

Rash accompanying a fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Complications of measles

A

-Giant cell pneumonia
-Post-infectious encephalitis
-Subacute sclerosing panencephalitis (SSPE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Koplik’s spot

A

Grans of salt surrounded by read halo on buccal mucosa in measles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Lab diagnostics for measles

A

ELISA (IgM)
Immunofluorescence
RT-PCR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ssRNA virus
Paramyxoviridae
Genus Morbillivirus

A

Measles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

ssRNA virus
Togaviridae
Genus rubivirius

A

Rubella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Prodromal phase symptoms of rubella

A

Fever
Malaise
Mild sore throat
Coryza

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Complications of Rubella

A

Arthralgia and arthritis
Congenital rubella syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Lab diagnostics for Rubella

A

ELISA (IgM)
Immunofluorescence
RT-PCR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Complication of Parvovirus B19 and cause

A

Aplastic crisis due to infection of erythroblast precursors in bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Complication of Parvovirus B19 in pregnant females

A

Hydrops fetalis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Lab diagnostics for Parvovirus B19

A

ELISA (IgM)
PCR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

dsDNA virus that multiplies in salivary gland and oropharynx

A

Roseola

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Rash that appears on trunk and neck first, then spreads to face, then to extremities

A

Roseola

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Infected cells show Cowdry type A intranuclear inclusions and form syncytia

A

VZV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Rash begins in hairline, scalp, and behind ears, then spreads to face, torso, and limbs

A

VZV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Serious complications in adult cases of VZV

A

Pneumonia
Encephalitis
Vigorous immune response

23
Q

Latent in dorsal root and cranial nerve ganglia

A

VZV

24
Q

Complications of herpes zoster

A

Postherpetic neuralgia
Ophthalmic zoster
Ramsey Hunt syndromes

25
Q

Pathogenesis of Ramsey Hunt syndromes

A

VZV travels down geniculate ganglion

26
Q

Symptoms of Ramsey Hunt syndromes

A

Otalgia
Hemiparesis
Vesicular eruption around the ear

27
Q

Characteristics of smallpox lesions

A

Synchronous
Concentrated on face and distal extremities

28
Q

HSV-1 enters latency here

A

Trigeminal ganglion

29
Q

Transmission of Coxsackie virus

A

Feco-oral

30
Q

Oral and pharyngeal ulcers, and vesicular rash on palms and soles with mild fever

A

Coxsackie/Hand-foot-mouth

31
Q

Laboratory diagnostic tests for vesicular rashes

A

Tzank smear
Immunofluorescence
ELISA
Immunohistochemistry
PCR (gold standard)

32
Q

Shown on Tzank smear for vesicular rashes

A

Multinucleated giant cells/syncytium
Viral inclusion bodies

33
Q

Used in acyclovir resistant vesicular viral rashes

A

Foscarnet
Cidofovir

34
Q

Can be used to prevent recurrence of viral vesicular rashes

A

Valacyclovir
Famciclovir

35
Q

Complication of roseola

A

Febrile seizures

36
Q

Causes of petechiae, purpura, and/or ecchymosis mucocutaneous lesions

A

Menigococcemia
RMSF/Rickettsia rickettsii
Dengue fever/flavivirus
Leptospiroses
Lyme disease/erythema chronicum migrans
Hantavirus/Bunyavirus

37
Q

Rash begins on wrists/hands and ankles/feet and spreads to trunk. It starts as maculopapular and becomes petechial/purpuric

A

Rocky mountain spotted fever

38
Q

Complications of RMSF

A

Splenomegaly
DIC
Shock
Death

39
Q

Enveloped, isosahedral with positive sense ssRNA spread by Aedes mosquito

A

Dengue fever

40
Q

Maculopapular and hemorrhagic rash, retro-orbital pain, muscle and joint pain with fever

A

Dengue fever

41
Q

Caused by Borrelia burgdorferi

A

Lyme disease

42
Q

Bulls-eye rash with fever, HA, and lymphadenopathy

A

Lyme disease

43
Q

Complications of Lyme disease

A

Meningitis
Encephalitis
Bell’s palsy
Arthralgia and arthritis

44
Q

Lab diagnostics for Lyme disease

A

ELISA
Immunofluorescence
Western blot
PCR

45
Q

Enveloped, negative sense, segemented, ssRNA in rodent excreta

A

Hantavirus/Bunyavirus

46
Q

Complications of hantavirus

A

HPS
HFRS

47
Q

Non-enveloped, circular dsDNA that replicates in basal keratinocytes

A

HPV

48
Q

Koilocytes

A

Enlarged keratinocytes with clear halos around shrunken nuclei that are characteristic of HPV infections

49
Q

Nodular to wart-like lesions that later become pearly-white umbilicated nodules with central caseous pus

A

Molluscum contagiosum virus

50
Q

Histology of molluscum bodies

A

Pink, homogenous, intracytoplasmic inclusions seen in biopsy specimens, or in the expressed caseous core of a nodule

51
Q

Mycolic acid in cell wall and acid fast bacilli

A

Mycobacterium leprae

52
Q

Transmission of leprosy

A

Inhalation and skin contact
Requires prolonged contact

53
Q
A

MSK II (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions