Zinc and Copper

Question 1

what is the 4th micronutrient of concern?

Answer 1

zinc

Question 2

deficiency seen in parts of world with:

Answer 2

unleavened bread (phytate), hot climate (sweat loss)

Question 3

unprocessed cereals have ____ inhibiting zinc absorption

Answer 3

phytates

Question 4

UL of zinc based on?

Answer 4

copper inhibition

Question 5

why do mature males need more Zn?

Answer 5

semen production

Question 6

oysters have __mg/100g Zn, meat hve ___mg/100g

Answer 6

90; 3-4

Question 7

a storage protein called _____ is made when Zn absorption in enterocyte increases

Answer 7

metallothionein

Question 8

functions of Zn:

Answer 8

metalooenzymes, structural, gene expression, SOD in cyto

Question 9

enzyme that gets rid of extra glutamic acids , need Zn

Answer 9

conjugase

Question 10

zinc ___ on DNA permit hormone binding

Answer 10

fingers

Question 11

EAR of Zn is based on _____ of zinc losses

Answer 11

factorial analysis

Question 12

vegetarians need __% more Zn

Answer 12

50

Question 13

why is it difficult to assess Zn status with plasma Zn lvl?

Answer 13

Zn redistributes (into liver when infection)

Question 14

signs of Zn deficiency?

Answer 14

collagen defects, dermatitis, poor growth in kids (decreased cell div), night blindness

Question 15

worst source of zinc?

Answer 15

fruits

Question 16

unusual features of Zn deficiency?

Answer 16

measure hair zinc, taste (hypoguesis), alopecia, slowed puberty in men

Question 17

interleukin-1 induces ____ synth

Answer 17

metallothionine

Question 18

eating clay/dirt is referred to as:

Answer 18

geophagia

Question 19

UL for Zn is ___mg

Answer 19

40 (food and supplements)

Question 20

how is copper excretion diff from Fe and Zn?

Answer 20

excretion is regulated by bile vs. ceruloplasmin

Question 21

form of copper needed convert Fe2–>Fe3

Answer 21

ceruloplasmin

Question 22

low copper can cause ___ anemia

Answer 22

microcytic

Question 23

copper containing metalloenzymes?

Answer 23

ceruloplasmin, SOD, lysyl oxidase

Question 24

RDA for copper is ___ mcg, and the EAR is based on:

Answer 24

900; maintaining normal plasma Cu and RBC SOD

Question 25

food sources of copper?

Answer 25

organ meats, shellfish, nuts, seeds, cocoa, cooking with copper pots, water in copper pipes

Question 26

deficiency symptoms for copper include:

Answer 26

microcytic hypochromic anemia, impaired immunity, depigmentation, heart disease

Question 27

what is copper UL?

Answer 27

10mg, causes liver damage

Question 28

genetic disease of abnormal Cu accumulation that can be treated with zinc, first a liver disease and then psych symptoms (then fatal)

Answer 28

Wilsons disease

Question 29

most characteristic sign of Wilsons disease?

Answer 29

Kayser-Fleischer ring (rusty brown ring around cornea of eye that can be seen thru eye exam)