B6

Question 1

B6 is referred to as:

Answer 1

pyridoxine

Question 2

animal food version of B6

Answer 2

pyridoxal

Question 3

animal based foods version of B6

Answer 3

pyridoxamine

Question 4

plant based food version of B6

Answer 4

pyridoxine

Question 5

main form of B6 coenzyme?

Answer 5

PLP

Question 6

need ____ enzyme to convert PMP/PNP –>PLP

Answer 6

FMN-dependent (need riboflavin)

Question 7

5 functions of B6?

Answer 7

1) transamination 2) decarboxylation 3) synth heme 4) TRP–> 5) synth of cysteine from MET via homocysteine

Question 8

PLP needed in ___–>oxaloacetate

Answer 8

aspartate

Question 9

alanine with amino group removed is:

Answer 9

pyruvate

Question 10

Vit B6 needed to form neurotrans such as:

Answer 10

serotonin, GABA

Question 11

protoporphyrin is made from this amino acid

Answer 11

glycine

Question 12

why is cysteine semi-indispensable?

Answer 12

we can make it, but we need a supply of MET, which is indispensable

Question 13

deficiency symptoms?

Answer 13

microcytic anemia, convulsions, depression/confusion, nerve damage, cardiovascular

Question 14

EAR set based on?

Answer 14

maintenance of normal PLP in plasma

Question 15

measuring plasma PLP is a _____ measure of stores

Answer 15

surrogate

Question 16

food sources B6?

Answer 16

whole grain, meat, milk

Question 17

what is functional test for B6?

Answer 17

production of abnormal metabolites (when PLP low); test w/ 2g TRP load

Question 18

abnormal metabolite examples

Answer 18

MMA, HCY, xanthurenic acid (in urine)

Question 19

B6 prescribed for these conditions

Answer 19

PMS, carpal tunnel, depression

Question 20

UL for B6 is for ___ sources; based on _____neuropathy

Answer 20

all; peripheral sensory

Question 21

symptoms of peripheral sensory neuropathy?

Answer 21

tingling/burning, clumsiness, ataxia, numbness in limbs

Question 22

UF of B6?

Answer 22

2