Vit D Flashcards
D3 is known as ____ while D2 is known as ___
cholecalciferol; ergocalciferol
the major circulating form of Vit D is ____; the active form is called _____
25(OH)D; calcitriol aka 1,25
___ path goes through kidney while ___ path goes through other tissues
endocrine; paracrine/autocrine
body’s need for more Ca is sensed by an ___ in ____ hormone; need for more phosphate is sensed by a ___ of ____
increase; PTH; decrease; FGF-23
the endocrine path targets ____ and ___
intestine; bone
calcitriol causes production of proteins that bind calcium, including:
calbindin, Ca channel, ATPase
this protein opens Ca channels in Brush border membrane
calbindin
DV is ___, EAR is ____, RDA is ___
5 mcg; 10mcg; 15mcg
what are food sources of vit D?
milk, orange juice, margarine, sardines and salmon
What does MED stand for?
minimal erythema dose (reddening of skin)
Vit D synth stops at about __ MED
1
everyone should take a supplement of ___ IU
400
UL is ____ IU; > ___ nmol/L not protective
4000 IU; 150
retinoic acid and 1,25 are both ____ factors
transcription