Phosphorus Flashcards
We consume and use P as:
PO4 -3 (Pi)–>inorganic phosphate
recommended dietary lvls are given as:
mgP
85% P found in ___, 15% in ___
bone; soft tissues (bound to many cules)–>regulatory
passive absorption through ___ has a ___% efficiency
diffusion; 70
___ absorption is ____ mediated, and has ___% efficiency
active; 1,25; 90
phosphates are dangerous for people with ___ failure
renal
This form is poorly digested, found in plant cell walls
phytate
active absorption of P is initiated by the _____ cotransporter
sodium phosphate (enhanced by calcitriol)
This substance enhances absorption of P
vitamin D
these substances inhibit absorption of P (we WANT this)
Mg, Ca, Al
What is the RDA of P?
700mg
what are food sources of P?
stuff with protein (meat, dairy, legumes, grains), additives for powdered foods and colas
The P in ___ is poorly absorbed
phytate
^1,25 causes ___ absorption of Pi
increased
PTH ____ urinary losses of Pi and bone losses of both Ca and Pi
increases (contrast from Ca)
what is the UL?
4000mg (elevated serum P–>bone loss, kidney failure)
RDA for Mg?
400 mg for males, 310 mg for females
what are some functions of Mg in body
bone, enzyme function, CNS
What is the best food source of Mg?
legumes (back beans)
channel for Mg in enterocyte is called ___ and channel for Ca is called ___
TRVM6; TRPV6
substances that enhance absorption of Mg?
Vitamin D, Protein, Carbs, Fructose, inulin (fermentable fibre)
substances that inhibit absorption of Mg?
phytic acid, fibre, f.a.
symptoms of this include insomnia, tremors, leg cramps
hypomagnesemia
symptoms of this include lethargy that leads to a coma
hypermagnesemia
Mg ___ w/ Ca in absorption, Mg ____ w/ Ca in plasma lvls, Mg ___ w/ Ca in intracellular
competes; complements; competes
Mg __ contraction of muscle, Ca ___ contraction
inhibits; causes
Mg causes ___, Ca causes ___
diarrhea; constipation
Mg ___ coagulation while Ca ___ coagulation
decreases; increases
UL is based on ___ intake; it is set at ___mg
acute (as a drug); 350
MgSO4 is ___, causing ^ GI transit time
cathartic