Wuchereria bancrofti Flashcards

1
Q

Wuchereria bancrofti. Other name

A

Bancroft’s filaria

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2
Q

Wuchereria bancrofti. Habitat:

A

Lymphatics

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3
Q

Wuchereria bancrofti. Vector:

A

Mosquito (Anopheles, Culex, Aedes)

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4
Q

Disease: Elephantiasis. What parasite

A

Wuchereria bancrofti

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5
Q

Wuchereria bancrofti. Disease:

A

Elephantiasis (lower) with chylocoele/hydrocoele and chyluria, Tropical Pulmonary eosinophilia

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6
Q

Wuchereria bancrofti. Microfilaria: size?

A

270 – 290 um

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7
Q

Wuchereria bancroft. Microfilaria: Highest concentration in nighttime, about ___ to ____ (same with B. malayi)

A

10pm to 2am

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8
Q

Wuchereria bancrofti. Microfilaria: Highest concentration in nighttime, about 10pm to 2am (same with ___)

A

Brugia malayi

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9
Q

Its microfilaria is a Minute snake like organisms in red
blood cells, “graceful appearance

A

Wuchereria bancrofti

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10
Q

Wuchereria bancrofti. Microfilaria is a Minute snake like organisms in red
blood cells, “____ appearance

A

graceful appearance

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11
Q

Wuchereria bancrofti. Adult: males sizes

A

20 – 40 mm in length and 100 um in width

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12
Q

Wuchereria bancrofti. Adult:
males: has a ventrally curved tail with how many pairs of caudal sensory organs

A

15 pairs

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13
Q

Wuchereria bancrofti. Adult: Female sizes

A

80-100 mm in length and 300 um in width

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14
Q

In this parasite, the adult - generally, are cylindrical, whitish and somehow transparent; they have a neck area

A

Wuchereria bancrofti

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15
Q

Maturation time of Wuchereria bancrofti

A

2-3 weeks

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16
Q

in Wuchereria bancrofti, the microfilariae appear in the blood ____ year after infection

A

1 year

17
Q

Wuchereria bancrofti. Presence of thousands to millions of microfilariae in peripheral blood with no
clinical manifestation

A

Asymptomatic

18
Q

Wuchereria bancrofti. Acute stage: early manifestations ___ and inflammation of lymph glands
(_____).

A

fever and inflammation of lymph glands
(lymphadenitis).

19
Q

Wuchereria bancrofti. what stage in pathogenesis, . Recurrent attacks are those involving funiculitis, swelling and redness of arms
and legs.

A

Acute stage

20
Q

Wuchereria bancrofti. Chronic pitting edema progressing into non pitting edema. Positive for fibrous hyperplasia. Lower elephantiasis may occur

A

Chronic stage/lymphedema

21
Q

Wuchereria bancrofti. PATHOGENESIS. Can stimulate apoptosis of dendritic cells and CD4+ T cells

A

Immunologic consequences

22
Q

Dreyer’s staging for chronic lymphedema. Swelling increases in day but disappears overnight (especially when lying in bed)

A

Stage 1

23
Q

Dreyer’s staging for chronic lymphedema. Swelling no longer reversible, occurrence of acute attacks and can have bad odor

A

Stage 2:

24
Q

Dreyer’s staging for chronic lymphedema. Presence of shallow skin folds, occasional acute attacks and bad odor

A

Stage 3

25
Q

Dreyer’s staging for chronic lymphedema. Knobs and protrusions are found in skin, occasional acute attacks and bad odor

A

Stage 4

26
Q

Dreyer’s staging for chronic lymphedema. Deep skin folding, frequent acute attacks and lymphedema can go beyond the knee

A

Stage 5

27
Q

Dreyer’s staging for chronic lymphedema. Mossy lesions (mossy foot), acute attacks and wounds in skin

A

Stage 6

28
Q

Dreyer’s staging for chronic lymphedema. hOW MANY STAGES

A

7 STAGES

29
Q

Wuchereria bancrofti. LABORATORY DIAGNOSIS. The diagnosis of filariasis depends on the clinical features, history of exposure in ____ and on laboratory findings.

A

endemic areas

30
Q

Wuchereria bancrofti. LABORATORY DIAGNOSIS. Microfilaria can be demonstrated in ___, ______, and ____.

A

blood, chylous urine exudate of lymph varix, and hydrocele fluid.

31
Q

Wuchereria bancrofti. LABORATORY DIAGNOSIS. specimen of choice

A

peripheral blood

32
Q

Wuchereria bancrofti. Biopsy:
_____ can be seen in sections of biopsied lymph nodes, but this is not employed in routine diagnosis

A

Adult filarial worms

33
Q

Wuchereria bancrofti.. Skin Test

A

Intradermal injection of filarial antigens

34
Q

Wuchereria bancrofti. Imaging technique

A

Ultrasonography
Radiology

35
Q

This is when Mosquitoes are allowed to feed on the infected patients and are dissected 4-6 weeks later to demonstrate microfilaria, useful in detecting low density microfilaremia

A

Xenodiagnosis

36
Q

Xenodiagnosis:
Mosquitoes are allowed to feed on the infected patients and are dissected ____ weeks later to demonstrate microfilaria, useful in detecting low density microfilaremia

A

4-6 weeks