Wuchereria bancrofti Flashcards

1
Q

Wuchereria bancrofti. Other name

A

Bancroft’s filaria

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2
Q

Wuchereria bancrofti. Habitat:

A

Lymphatics

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3
Q

Wuchereria bancrofti. Vector:

A

Mosquito (Anopheles, Culex, Aedes)

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4
Q

Disease: Elephantiasis. What parasite

A

Wuchereria bancrofti

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5
Q

Wuchereria bancrofti. Disease:

A

Elephantiasis (lower) with chylocoele/hydrocoele and chyluria, Tropical Pulmonary eosinophilia

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6
Q

Wuchereria bancrofti. Microfilaria: size?

A

270 – 290 um

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7
Q

Wuchereria bancroft. Microfilaria: Highest concentration in nighttime, about ___ to ____ (same with B. malayi)

A

10pm to 2am

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8
Q

Wuchereria bancrofti. Microfilaria: Highest concentration in nighttime, about 10pm to 2am (same with ___)

A

Brugia malayi

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9
Q

Its microfilaria is a Minute snake like organisms in red
blood cells, “graceful appearance

A

Wuchereria bancrofti

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10
Q

Wuchereria bancrofti. Microfilaria is a Minute snake like organisms in red
blood cells, “____ appearance

A

graceful appearance

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11
Q

Wuchereria bancrofti. Adult: males sizes

A

20 – 40 mm in length and 100 um in width

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12
Q

Wuchereria bancrofti. Adult:
males: has a ventrally curved tail with how many pairs of caudal sensory organs

A

15 pairs

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13
Q

Wuchereria bancrofti. Adult: Female sizes

A

80-100 mm in length and 300 um in width

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14
Q

In this parasite, the adult - generally, are cylindrical, whitish and somehow transparent; they have a neck area

A

Wuchereria bancrofti

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15
Q

Maturation time of Wuchereria bancrofti

A

2-3 weeks

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16
Q

in Wuchereria bancrofti, the microfilariae appear in the blood ____ year after infection

17
Q

Wuchereria bancrofti. Presence of thousands to millions of microfilariae in peripheral blood with no
clinical manifestation

A

Asymptomatic

18
Q

Wuchereria bancrofti. Acute stage: early manifestations ___ and inflammation of lymph glands
(_____).

A

fever and inflammation of lymph glands
(lymphadenitis).

19
Q

Wuchereria bancrofti. what stage in pathogenesis, . Recurrent attacks are those involving funiculitis, swelling and redness of arms
and legs.

A

Acute stage

20
Q

Wuchereria bancrofti. Chronic pitting edema progressing into non pitting edema. Positive for fibrous hyperplasia. Lower elephantiasis may occur

A

Chronic stage/lymphedema

21
Q

Wuchereria bancrofti. PATHOGENESIS. Can stimulate apoptosis of dendritic cells and CD4+ T cells

A

Immunologic consequences

22
Q

Dreyer’s staging for chronic lymphedema. Swelling increases in day but disappears overnight (especially when lying in bed)

23
Q

Dreyer’s staging for chronic lymphedema. Swelling no longer reversible, occurrence of acute attacks and can have bad odor

24
Q

Dreyer’s staging for chronic lymphedema. Presence of shallow skin folds, occasional acute attacks and bad odor

25
Dreyer's staging for chronic lymphedema. Knobs and protrusions are found in skin, occasional acute attacks and bad odor
Stage 4
26
Dreyer's staging for chronic lymphedema. Deep skin folding, frequent acute attacks and lymphedema can go beyond the knee
Stage 5
27
Dreyer's staging for chronic lymphedema. Mossy lesions (mossy foot), acute attacks and wounds in skin
Stage 6
28
Dreyer's staging for chronic lymphedema. hOW MANY STAGES
7 STAGES
29
Wuchereria bancrofti. LABORATORY DIAGNOSIS. The diagnosis of filariasis depends on the clinical features, history of exposure in ____ and on laboratory findings.
endemic areas
30
Wuchereria bancrofti. LABORATORY DIAGNOSIS. Microfilaria can be demonstrated in ___, ______, and ____.
blood, chylous urine exudate of lymph varix, and hydrocele fluid.
31
Wuchereria bancrofti. LABORATORY DIAGNOSIS. specimen of choice
peripheral blood
32
Wuchereria bancrofti. Biopsy: _____ can be seen in sections of biopsied lymph nodes, but this is not employed in routine diagnosis
Adult filarial worms
33
Wuchereria bancrofti.. Skin Test
Intradermal injection of filarial antigens
34
Wuchereria bancrofti. Imaging technique
Ultrasonography Radiology
35
This is when Mosquitoes are allowed to feed on the infected patients and are dissected 4-6 weeks later to demonstrate microfilaria, useful in detecting low density microfilaremia
Xenodiagnosis
36
Xenodiagnosis: Mosquitoes are allowed to feed on the infected patients and are dissected ____ weeks later to demonstrate microfilaria, useful in detecting low density microfilaremia
4-6 weeks