RHIZOPODIA Flashcards
pathogenic free living amoeba
Rhizopodia
Acanthamoeba species was discovered by
Aldo Castellani
Has a spine-like psuedopods
Acanthamoeba species
tagged as the “ Trojan hose” of the microbial world as it harbours many organisms which is endosymbiotic in nature
Acanthamoeba species
Acanthamoeba species PROTOZOAN
Cryptosporidium spp. and Toxoplasma gondii
Acanthamoeba species. Trophozoite: measure
25-40 um
Acanthamoeba species. Cyst: measures
13-20 um
Acanthamoeba species. Infective and diagnostic stage
Trophozoite
Acanthamoeba species. POE
Eyes, Nose, Skin, Bloodstream, Brain
Acanthamoeba species. Disease:
Immunocompromised
Granulomatous amoebic encephalitis
Acanthamoeba species. Disease: Immunocompetent:
Corneal ulcer/ Acanthamoebic keratitis
CSF shows lymphocytic pleocytosis, slightly elevated protein levels, and normal or slightly decreased glucose levels.
Granulomatous amoebic encephalitis
diagnosed by epithelial biopsy or corneal scrapings for recoverable ameba with characteristic staining patterns on histologic analysis
Corneal ulcer/ Acanthamoebic keratitis
Acanthamoeba species. Diagnosis. Gold standard:
Calcofluor white (stain)
Acanthamoeba species. Prevention and Control
Meticulous contact lens hygiene is essential in avoiding infection, and rinsing contact lenses in tap water should be avoided.
administered in Acanthamoeba keratitis
Biguanide, chlorhexidine
Patient often experience smell and taste alteration, blocked nose. It is diagnostic sign for meningitis
Kernig’s sign
Acanthamoeba species. : surgery in severe cases where vision is threatened
Keratoplasty