B. malayi & O. volvulus

Question 1

Brugia malayi
Other name:

Answer 1

Malarian filaria

Question 2

Brugia malayi. Habitat:

Answer 2

Lymphatics

Question 3

Brugia malayi. Vector: Mosquito (_____)

Answer 3

Mansonia

Question 4

What parasite? Disease: Elephantiasis (upper) with chylocoele/hydrocoele and w/ ochyluria, Immunosuppression inducing apoptosis of CD4+ cells

Answer 4

Brugia malayi

Question 5

Brugia malayi. Microfilaria:
Size?

Answer 5

111 – 230 um

Question 6

Brugia malayi. Adult:
males size

Answer 6

13-23 mm length, 70- 80 um in width

Question 7

Brugia malayi. Adult: females size?

Answer 7

43-55 mm in length, 130-170 um in width

Question 8

Generally, resemble Wuchereria bancrofti but are smaller

Answer 8

Adult, Brugia malayi

Question 9

B. malayi can potentially suppress ____ functions

Answer 9

T cell functions

Question 10

B. malayi microfilariae best method for diagnosis

Answer 10

examination of stained blood films

Question 11

B. malayi. Treatment.

Answer 11

diethylcarbamazine

Question 12

Onchocerca volvulus
Other name:

Answer 12

Convoluted filaria, Blinding worm

Question 13

Onchocerca volvulus. Habitat:

Answer 13

Subcutaneous tissue

Question 14

Onchocerca volvulus. Vector:

Answer 14

Blackfly/Buffalo gnat (Simulium damnosum)`

Question 15

What parasite? Disease: Blinding filariasis, River blindness, Onchocercomata, Hanging groin, Leopard skin

Answer 15

Onchocerca volvulus

Question 16

Onchocerca volvulus. Microfilaria:
Size?

Answer 16

220-360 um in length and 5-9 um in width

Question 17

Onchocerca volvulus Microfilaria:
220-360 um in length and 5-9 um in width, can persist for ___ in host

Answer 17

2 years

Question 18

Onchocerca volvulus Microfilaria: Usually deposited in ____, ___ or _____

Answer 18

eyes, skin or lymph nodule

Question 19

Onchocerca volvulus. Adults: Males size?

Answer 19

19-42 mm in length, 130-210 um in width

Question 20

Onchocerca volvulus. Adults: Females size

Answer 20

33-50cminlength,270-400 um in width

Question 21

what parasite Adults: Wirelike and whitish in appearance

Answer 21

Onchocerca volvulus

Question 22

O. volvulus. They are occasionally found in peripheral blood, urine, and sputum but are typically found
in the __ and in the___ of connective tissues

Answer 22

skin and in the lymphatics

Question 23

O. volvulus can promote Mycobacterium ____ and Mycobacterium ______

Answer 23

Mycobacterium leprae and Mycobacterium tuberculosis

Question 24

chronic onchocerca * dermatitis

Answer 24

, lizard/ leopard skin

Question 25

(localized onchocercal dermatitis, autoantibodies against defensin

Answer 25

“sowda”

Question 26

O. volvulus. LABORATORY DIAGNOSIS: horizontal slices of 1.5 mg or 2 mm or 4 mm in epidermis (treated with volatile agent, tissue is treated with saline and stained with hematoxylin and eosin)

Answer 26

Skin snips/skin biopsies

Question 27

Skin snips/skin biopsies: horizontal slices of 1.5 mg or 2 mm or 4 mm in _____

Answer 27

epidermis

Question 28

Done only in skin infections, topical application of 1.6% DEC leads to local reaction, OR; initial 50 mg DEC is given orally then after 2 hours, intense pruritus of patients suggest onchocerciasis

Answer 28

Mazzoti skin test:

Question 29

O. volvulus Treatment

Answer 29

ivermectin, suramin (heavy infections)