M2 BABESIA

Question 1

Resemble plasmodium with no malarial pigments

Answer 1

Babesia microti

Question 2

Causes tickborne malaria like illness on domestic and wild animals

Answer 2

Babesia microti

Question 3

Causes opportunistic infection on humans

Answer 3

Babesia microti

Question 4

B. microti is named after

Answer 4

Babes

Question 5

In 1888, described the intraerythrocytic parasite in the blood of cattle and ship

Answer 5

Babes

Question 6

First arthropod-borne disease

Answer 6

B.microti

Question 7

Definitive host of B. microti

Answer 7

Ixoxid tick

Question 8

Intermidiate host of B. microti

Answer 8

Mammals

Question 9

B. microti can be transmitted through ___ & ___

Answer 9

Blood transfusion and placentally

Question 10

Infective form of B. microti in human

Answer 10

Sporozoite

Question 11

MOT: bite of ___ stage of ixoxid ticks

Answer 11

Nymphal stage

Question 12

Size of tropozoite in B. microti

Answer 12

2-5 um

Question 13

Trophozoite of B. microti found in

Answer 13

Red cells

Question 14

B. microti, Shape may be pyriform, ameboid, spindle like

Answer 14

Trophozoite

Question 15

B. microti, spherical or oval

Answer 15

Merozoite

Question 16

2 host of B. microti

Answer 16

1. White footed rodent
2. Ixodes tick

Question 17

Sporozoite undergo asexual reproduction called

Answer 17

Budding

Question 18

Infected ticks introduces ___ into the human host

Answer 18

Sporozoite

Question 19

Vertical heriditary transmission. Has been documented for large babesia spp but not for small babesia spp like B.microti

Answer 19

Transovarial transmission

Question 20

Dead end host of B.microti

Answer 20

Human

Question 21

Primarily responsible for many clinical manifestation

Answer 21

Hemolysis of infected erythrocyte

Question 22

Illness develops how many weeks after tick bites . B.microti

Answer 22

1-6 weeks

Question 23

B.microti fever exceeds

Answer 23

38° - 40.6°

Question 24

Sever babesiosis is associated with parasitemia levels of more than ___ infected RBC’s

Answer 24

4%

Question 25

Fatality rate B.microti

Answer 25

5%

Question 26

Fatality rate immunocompromised. B.microti

Answer 26

20%

Question 27

Complications of acute babesiosis

Answer 27

1. Acute renal failure 2. Disseminated intravascular coagulation 3. Acute respiratory distress syndrome 4. Congested cardiac failure

Question 28

Stain B.microti

Answer 28

Giemsa and Leishman

Question 29

Distinguished features of B.microti

Answer 29

Presence of tetrads

Question 30

Maltose crosses

Answer 30

Tetrads

Question 31

Serology of B.microti, useful in conforming disease

Answer 31

Indirect immunofluroscent antibody (IFA)

Question 32

___ count is elevated. B.microti

Answer 32

Reticulocyte

Question 33

___ is common. B.microti

Answer 33

Thrombocytopenia

Question 34

___ count may be normal or slightly decreases

Answer 34

WBC

Question 35

B.microti. liver function test

Answer 35

Serum glutamic pyruvate transaminase (SGPT)

Question 36

Application of bug repellents like DEET ?

Answer 36

N,N-diethyl-meta-toluamide

Question 37

In renal complicarions, ___ are found

Answer 37

Bloor urea nitrogen and serum creatinine