Weight Loss Flashcards

1
Q

OP is a 42 y/o male, height 5’10”, weight 198 pounds. He has a PMH of hypothyroidism, seizure disorder, and depression. He takes the following meds: VPA, olanzapine, topiramate, levothyroxine, aspirin, omeprazole, mirtazapine, and ibuprofen PRN. Which of his conditions or meds can cause weight loss?

a. Mirtazapine
b. Olanzapine
c. Hypothyroidism
d. Valproic acid
e. Topiramate

A

e

All other options cause weight gain.

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2
Q

What are the 2 most important monitoring parameters for a pt taking a stimulant weight loss (e.g., phentermine or phentermine/topiramate)?

a. Stool frequency and peripheral edema
b. HR and BP
c. Respiratory rate and migraine symptoms
d. Sleep patterns and blood glucose
e. Blood glucose and lipid panel

A

b

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3
Q

MS is a 44 y/o female. Height 5’7”, weight 178 pounds. Her PMH includes T2DM and HTN. Her BP this morning 134/78, and labs from last month included A1C of 8.7% and total cholesterol of 244 g/dL. MS consumes a primarily carb-based diet with little veggie intake. She tried OTC weight loss products without success. Which of the following drugs is indicated for both weight loss and diabetes?

a. Liraglutide
b. Orlistat
c. Phentermine/topiramate
d. Phentermine
e. Naltrexone/bupropion

A

a

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4
Q

Complications of being overweight include the following:

a. Coronary heart disease
b. Type 2 diabetes
c. HTN
d. Stroke
e. Alopecia

A

a, b, c, d

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5
Q

A 19 y/o female is diagnosed with depression and obesity and is asking for an Rx drug for weight loss. Which med should be avoided in this pt?

a. Liraglutide
b. Orlistat
c. Diethylpropion
d. Naltrexone/bupropion
e. Phentermine/topiramate

A

d

Antidepressants, such as bupropion, can increase the risk of suicidal thinking and behavior in young adults and adolescents.

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6
Q

Which of the following drugs for weight loss can be used long-term for weight maintenance?

a. Adipex-P
b. Alli
c. Saxenda
d. Phentermine/topiramate
e. Naltrexone/bupropion

A

b, c, d, e

Phentermine (Adipex-P) is a short-term stimulant appetite suppressant that can “jump start” weight loss, but it shouldn’t be used long-term.

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7
Q

What is the scheduled (DEA) category of Qsymia?

a. CII
b. CIII
c. CIV
d. CV
e. It’s not scheduled.

A

c

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8
Q

HPI: BH is a 56 y/o female who presents to the clinic in October for an evaluation, so she can quit smoking. The pharmacist reviews her profile before starting the visit.

Allergies: Wellbutrin (seizures)

PMH: Depression

Smoking hx: Smoked 1.5 packs per day for the last 19 years. First cigarette usually smoked 10 minutes after waking up when she has her morning coffee.

Height: 5’5”, weight: 186 pounds

Home meds: Lexapro 20 mg PO daily

Additional notes: BH is concerned that she’ll gain more weight when she stops smoking. She’s already overweight and struggles because of her depression.

BH is willing to engage in a dietary plan and physical activity program for weight loss. Which additional criteria does BH meet for an Rx weight loss drug?

a. Her BMI is > 30 with no other weight-related condition
b. Her BMI is > 25 + diagnosed with depression
c. Her BMI is > 27 + one other weight-related condition
d. Her BMI is > 35 + one other weight-related condition
e. She has a small of weight to lose to attain her ideal BMI

A

a

The Rx drugs should be used only in addition to changes in diet and increased physical activity and only in patients with higher BMIs (> 27 if there are other health complications or > 30 without). BH has a BMI of 30.9. Rx drugs shouldn’t be used in pts unable to engage in a dietary plan and physical activity program and if a small amount of weight loss is needed (< 10 pounds).

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9
Q

HPI: BH is a 56 y/o female who presents to the clinic in October for an evaluation, so she can quit smoking. The pharmacist reviews her profile before starting the visit.

Allergies: Wellbutrin (seizures)

PMH: Depression

Smoking hx: Smoked 1.5 packs per day for the last 19 years. First cigarette usually smoked 10 minutes after waking up when she has her morning coffee.

Height: 5’5”, weight: 186 pounds

Home meds: Lexapro 20 mg PO daily

Additional notes: BH is concerned that she’ll gain more weight when she stops smoking. She’s already overweight and struggles because of her depression.

BH is prescribed orlistat for weight loss. Which of the following statements on orlistat administration is correct?

a. Take with a high-calorie snack (at least 50% kilocalories from fat)
b. Take with a high-fat diet plan
c. Take with a high-fiber meal, high-carb diet plan
d. Take with a multivitamin containing A, D, E, and K at a different time of day
e. Take at the same time as a multivitamin containing A, D, E, and K

A

d

Orlistat is a lipase inhibitor that decreases the absorption of dietary fats. Pts must be on a low-fat diet (maximum of 30% calories from fat) while using this drug. Multivitamins containing vitamin A, D, E, and K should be taken at bedtime or separated by at least 2 hours from orlistat.

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