Benign Prostatic Hyperplasia (BPH) Flashcards
JB is a 75 y/o male who’s starting Flomax. Choose the correct starting dose.
a. 0.4 mg daily
b. 1 mg at bedtime
c. 4 mg daily
d. 5 mg daily
e. 10 mg at bedtime
a
Which best represents the time required for dutasteride to reach maximal effect?
a. 3-7 days
b. 2-3 weeks
c. 4-6 weeks
d. 2-3 months
e. 6 months or longer
e
5 alpha-reductase inhibitors have a delayed onset of 6 months or longer (it takes times to decrease prostate size).
Which best describes the MOA of Proscar?
a. Inhibits 5 alpha-reductase
b. Inhibits phosphodiesterase-5
c. Selectively blocks alpha-1A receptors
d. Dilates the urethra
e. Non-selectively blocks alpha-1 receptors
a
Proscar = finasteride
Use of terazosin increases the risk of which complication during cataract surgery?
a. Increased intraocular pressure
b. Intraoperative floppy iris syndrome
c. Temporary vision loss
d. Retinal detachment
e. Nonarteritic anterior ischemic optic neuropathy
b
Alpha-1 blockers have been associated with intraoperative floppy iris syndrome during cataract surgery d/t relaxation of the dilator muscle in the eye.
Which med used for the tx of BPH is contraindicated with isosorbide dinitrate?
a. Doxazosin
b. Silodosin
c. Finasteride
d. Tadalafil
e. Alfuzosin
d
A pt taking tadalafil should be counseled to report serious side effects, which can include:
a. Ringing in the ears
b. Vision loss
c. An erection lasting more than 4 hours
d. Chest pain
e. Decreased libido
a, b, c, d, e
Tadalafil has warnings for hearing loss (with or without tinnitus), vision loss (which can be d/t NAION), impaired color discrimination, priapism, and cardiac side effects (d/t vasodilation).
BPH typically causes LUTS, which can include:
a. Frequent urination
b. Urine leaking
c. Pain and burning on urination
d. Blood in the urine
e. Weak urine stream
a, b, e
Lower urinary tract symptoms (LUTS) common with BPH include urinary hesitancy, intermittent, straining or a weak urine stream, urinary urgency, leaking/dribbling, incomplete bladder emptying, frequent urination, nocturia, and bladder outlet obstruction. Painful urination and blood in the urine are not common and would require further evaluation.
TL is a 53 y/o male currently taking the following meds and supplements: Metformin, glipizide, lisinopril, rosuvastatin, fish oil, magnesium, saw palmetto, cinnamon, and turmeric. Which natural product is TL most likely taking for symptoms of BPH?
a. Cinnamon
b. Fish oil
c. Magnesium
d. Saw palmetto
e. Turmeric
d
Saw palmetto is used but is likely ineffective for BPH.
Which diagnostic tests are routinely performed when a male presents with an enlarged prostate?
a. Creatinine phosphokinase (CPK) and transurethral ultrasound
b. Prostate-specific antigen (PSA) and digital rectal exam (DRE)
c. Transurethral resection of the prostate (TURP) and C-peptide
d. Fecal occult blood test (FOBT) and testosterone levels
e. Urinalysis and estimated GFR
b
These are important to rule out prostate cancer.
