Overactive Bladder Flashcards
There are different types of incontinence. Younger women predominantly have a problem with leakage of urine when they laugh, sneeze, cough, jog, or lift something heavy. What is the term for this type of incontinence?
a. Overflow
b. Mixed
c. Urge
d. Stress
e. Functional
d
Results when the muscles and tissue that help support the bladder become weak. The muscles can be strengthened with exercise.
Which of the following agents used for urge incontinence comes in a PO form, a transdermal patch, and a topical gel?
a. Oxybutynin
b. Solifenacin
c. Trospium
d. Darifenacin
e. Tolterodine
a
Older women predominantly have a problem with a sudden need to use the restroom, which can result in leakage of a larger amount of urine. What is the term for this type of incontinence?
a. Overflow
b. Mixed
c. Urge
d. Stress
e. Functional
c
Urge incontinence is associated with neuropathy and is common in pts with diabetes, stroke, dementia, Parkinson disease, or MS. The term “overflow incontinence” is used primarily for BPH.
Drugs used for urge incontinence bind to a specific subtype of anticholinergic receptor. Choose the correct statement concerning the receptor:
a. These drugs bind primarily to the nicotinic N2 receptor on the bladder muscle wall.
b. These drugs bind primarily to the nicotinic N3 receptor on the bladder muscle wall.
c. These drugs bind primarily to the muscarinic M2 receptor on the bladder muscle wall.
d. These drugs bind primarily to the muscarinic M1 receptor on the bladder muscle wall.
e. These drugs bind primarily to the muscarinic M3 receptor on the bladder muscle wall.
e
JF is a 55 y/o female who continues to have symptoms of urge incontinence despite combo therapy with Vesicare 10 mg PO daily and mirabegron 50 mg PO daily for the last 3 months. Which of the following tx options that has higher efficacy should be considered next?
a. Furosemide
b. Botox
c. Desmopressin
d. Detrol
e. There are no additional tx options available for urge incontinence.
b
Botox is considered after patients have failed 1st and 2nd line treatment options (i.e., anticholinergics and beta-3 agonists).
A female with OAB has been prescribed darifenacin once daily. Choose the correct statements concerning darifenacin:
a. Darifenacin works by activating the beta-3 receptors on the detrusor muscle.
b. Darifenacin is available in an injectable form.
c. The most common side effects are dry mouth and constipation.
d. Caution should be used if performing tasks that require mental alertness.
e. Darifenacin should be emptied into a glass of water, stirred, and drank immediately.
c, d
JF is a 40 y/o female who has complained of poor sleep because she has to get up to urinate at least twice every night. After discussion, the pt agrees to try a new Rx for desmopressin (Stimate). Which of the following is true?
a. Vasopressin
b. Stimate is a diuretic hormone.
c. Stimate can cause hyponatremia.
d. Stimate can cause hypokalemia.
e. Weight loss is common with this med.
c
Stimate contains desmopressin in a nasal spray formulation for tx of nocturia. It temporarily decreases urine production and carries a BBW for hyponatremia, which is dilutional. Monitor serum sodium levels.
